STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lepB-2KEGG: cac:CAC1760 4.2e-30 signal peptidase I K03100; COG: COG0681 Signal peptidase I; Psort location: CytoplasmicMembrane, score: 9.82; Belongs to the peptidase S26 family. (187 aa)    
Predicted Functional Partners:
lepB-3
Signal peptidase I; KEGG: ctc:CTC01253 3.7e-22 putative signal peptidase I K03100; COG: COG0681 Signal peptidase I; Belongs to the peptidase S26 family.
 
 
 
0.949
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
    0.915
lepB
Signal peptidase I; KEGG: mta:Moth_0972 1.2e-34 peptidase S26A, signal peptidase I K03100; COG: COG0681 Signal peptidase I; Psort location: CytoplasmicMembrane, score: 9.82.
 
  
 
0.857
EDR47189.1
TIGR00252 family protein; KEGG: sat:SYN_00772 9.9e-22 endonuclease; COG: COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Psort location: Cytoplasmic, score: 8.87; Belongs to the UPF0102 family.
  
    0.838
ylqF
Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
  
    0.775
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
 
 
 0.686
atpB-2
ATP synthase alpha/beta family, nucleotide-binding domain protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.
   
 
  0.668
atpB-3
ATP synthase ab domain protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.
   
 
  0.668
EDR47188.1
Conserved hypothetical protein, YfiH family; COG: COG1496 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87; Belongs to the multicopper oxidase YfiH/RL5 family.
  
    0.664
rseP
RIP metalloprotease RseP; KEGG: cac:CAC1796 6.3e-59 predicted membrane-associated Zn-dependent protease; COG: COG0750 Predicted membrane-associated Zn-dependent proteases 1; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.655
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.