STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
cobB-2Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. (240 aa)    
Predicted Functional Partners:
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.940
deoD
KEGG: bcl:ABC4021 8.9e-76 deoD; purine-nucleoside phosphorylase K03784; COG: COG0813 Purine-nucleoside phosphorylase; Psort location: Cytoplasmic, score: 8.87.
    
 0.919
EDR47904.1
NADH pyrophosphatase zinc ribbon domain protein; KEGG: lpl:lp_3123 8.2e-50 pyrophosphatase (putative) K03659; COG: COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Psort location: Cytoplasmic, score: 8.87.
   
  0.910
EDR46566.1
Acetyltransferase, GNAT family; KEGG: ldb:Ldb1165 2.0e-53 acyltransferase K00680; COG: COG1247 Sortase and related acyltransferases; Psort location: Cytoplasmic, score: 8.87.
  
    0.801
EDR47700.1
Glu/Leu/Phe/Val dehydrogenase, dimerization domain protein; KEGG: lsl:LSL_1297 1.5e-192 gdhA; NADP-specific glutamate dehydrogenase K00262; COG: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Psort location: Cytoplasmic, score: 9.98; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.785
EDR46989.1
Isocitrate dehydrogenase, NADP-dependent; KEGG: tte:TTE0387 7.5e-159 icd; Isocitrate dehydrogenases K00031; COG: COG0538 Isocitrate dehydrogenases; Psort location: Cytoplasmic, score: 8.87; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
    
  0.748
EDR46564.1
KEGG: ava:Ava_3074 6.5e-25 HAD-superfamily hydrolase subfamily IA, variant 3 K01838; COG: COG0637 Predicted phosphatase/phosphohexomutase; Psort location: Cytoplasmic, score: 8.87.
       0.746
EDR45655.1
Topoisomerase DNA-binding C4 zinc finger domain protein; KEGG: pab:PAB1430 5.2e-06 topA; DNA topoisomerase I K03168; COG: COG0514 Superfamily II DNA helicase; Psort location: Cytoplasmic, score: 8.87.
  
   0.743
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.681
EDR46567.1
CAAX amino terminal protease family protein; COG: COG1668 ABC-type Na+ efflux pump, permease component; Psort location: CytoplasmicMembrane, score: 9.99.
       0.668
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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