Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EDR46567.1CAAX amino terminal protease family protein; COG: COG1668 ABC-type Na+ efflux pump, permease component; Psort location: CytoplasmicMembrane, score: 9.99. (324 aa)    
Predicted Functional Partners:
accD
acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
  
    0.747
cobB-2
Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
       0.668
EDR46566.1
Acetyltransferase, GNAT family; KEGG: ldb:Ldb1165 2.0e-53 acyltransferase K00680; COG: COG1247 Sortase and related acyltransferases; Psort location: Cytoplasmic, score: 8.87.
       0.661
EDR46564.1
KEGG: ava:Ava_3074 6.5e-25 HAD-superfamily hydrolase subfamily IA, variant 3 K01838; COG: COG0637 Predicted phosphatase/phosphohexomutase; Psort location: Cytoplasmic, score: 8.87.
       0.639
EDR47722.1
Hypothetical protein; COG: COG0842 ABC-type multidrug transport system, permease component; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.634
EDR47723.1
Hypothetical protein; COG: COG0842 ABC-type multidrug transport system, permease component; Psort location: CytoplasmicMembrane, score: 9.99.
  
  
 0.634
EDR46568.1
Acetyltransferase, GNAT family; KEGG: dre:393677 2.8e-08 aanat1; arylalkylamine N-acetyltransferase 1 K00669; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: Cytoplasmic, score: 8.87.
       0.545
EDR46569.1
Hypothetical protein.
       0.545
EDR46563.1
Transcriptional regulator, MarR family; COG: COG1846 Transcriptional regulators; Psort location: Cytoplasmic, score: 8.87.
       0.520
accB-2
acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
     0.486
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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