Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pncBNicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (484 aa)    
Predicted Functional Partners:
nadC
Nicotinate-nucleotide diphosphorylase (carboxylating); KEGG: fnu:FN0010 1.8e-84 nicotinate-nucleotide pyrophosphorylase K00767; COG: COG0157 Nicotinate-nucleotide pyrophosphorylase; Psort location: Cytoplasmic, score: 8.87; Belongs to the NadC/ModD family.
   
 0.978
deoD
KEGG: bcl:ABC4021 8.9e-76 deoD; purine-nucleoside phosphorylase K03784; COG: COG0813 Purine-nucleoside phosphorylase; Psort location: Cytoplasmic, score: 8.87.
     
 0.920
EDR47904.1
NADH pyrophosphatase zinc ribbon domain protein; KEGG: lpl:lp_3123 8.2e-50 pyrophosphatase (putative) K03659; COG: COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Psort location: Cytoplasmic, score: 8.87.
    
 0.910
ddl
D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
       0.750
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
       0.745
EDR46584.1
KEGG: bcz:BCZK5094 7.1e-51 hydrolase, haloacid dehalogenase-like family K01564; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87.
       0.722
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.721
EDR45686.1
Bacterial capsule synthesis protein; COG: COG2843 Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation).
  
    0.713
EDR46581.1
Hypothetical protein.
       0.692
EDR46582.1
Branched-chain amino acid transport protein (AzlD); COG: COG4392 Predicted membrane protein; Psort location: CytoplasmicMembrane, score: 9.99.
       0.692
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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