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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR46664.1Resolvase, N-terminal domain protein; COG: COG1961 Site-specific recombinases, DNA invertase Pin homologs; Psort location: Cytoplasmic, score: 8.87. (221 aa)    
Predicted Functional Partners:
EDR46665.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.623
EDR46666.1
Hypothetical protein.
       0.616
EDR46667.1
Toxin-antitoxin system, toxin component, HicA family; Psort location: Cytoplasmic, score: 8.87.
       0.614
EDR46668.1
Toxin-antitoxin system, antitoxin component, HicB family; COG: NOG14977 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
       0.614
EDR48094.1
Hypothetical protein; COG: COG5484 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
   
    0.512
EDR46663.1
Transcriptional regulatory protein, C-terminal domain protein; KEGG: ava:Ava_1878 6.0e-08 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.65.
       0.444
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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