STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR46670.1Hypothetical protein. (157 aa)    
Predicted Functional Partners:
EDR48140.1
Hypothetical protein; KEGG: bca:BCE_0840 6.5e-16 type I restriction-modification system, R subunit K01153; COG: COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.846
EDR46671.1
Hypothetical protein; KEGG: vpa:VPA0006 1.1e-17 GTP cyclohydrolase II K01497; COG: COG3236 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
       0.731
EDR48452.1
COG: COG3943 Virulence protein; Psort location: Cytoplasmic, score: 8.87.
  
    0.651
ligA-2
DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
       0.621
EDR46669.1
Hypothetical protein; COG: COG1373 Predicted ATPase (AAA+ superfamily); Psort location: Cytoplasmic, score: 8.87.
       0.570
FbpA
COG: COG1293 Predicted RNA-binding protein homologous to eukaryotic snRNP; Psort location: Cytoplasmic, score: 8.87.
  
    0.548
EDR45509.1
Hypothetical protein; COG: COG1106 Predicted ATPases; Psort location: Cytoplasmic, score: 8.87.
  
    0.546
EDR46752.1
COG: COG1715 Restriction endonuclease; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.504
EDR48450.1
KEGG: hpa:HPAG1_1053 7.8e-26 excinuclease ABC subunit B; COG: COG0556 Helicase subunit of the DNA excision repair complex.
    
 
 0.489
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.489
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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