Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDR46671.1Hypothetical protein; KEGG: vpa:VPA0006 1.1e-17 GTP cyclohydrolase II K01497; COG: COG3236 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. (182 aa)    
Predicted Functional Partners:
EDR46349.1
ThiF family protein; KEGG: hpa:HPAG1_0799 3.4e-60 thiamine biosynthesis protein; COG: COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2; Psort location: Cytoplasmic, score: 8.87.
    
  0.747
EDR46670.1
Hypothetical protein.
       0.730
ligA-2
DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
       0.671
EDR46669.1
Hypothetical protein; COG: COG1373 Predicted ATPase (AAA+ superfamily); Psort location: Cytoplasmic, score: 8.87.
 
     0.611
EDR47337.1
Von Willebrand factor type A domain protein; KEGG: cal:orf19.1648 0.00031 RAD50; DNA repair protein K01553; COG: COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain.
  
     0.497
EDR46696.1
Hypothetical protein; COG: COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component; Psort location: CytoplasmicMembrane, score: 9.99.
  
     0.454
EDR46673.1
Hypothetical protein.
       0.437
EDR46796.1
Exonuclease; KEGG: psp:PSPPH_1792 4.5e-09 exonuclease; COG: COG5018 Inhibitor of the KinA pathway to sporulation, predicted exonuclease; Psort location: Cytoplasmic, score: 8.87.
  
     0.420
EDR47917.1
Oxidoreductase, aldo/keto reductase family protein; KEGG: ava:Ava_3100 2.1e-44 aldo/keto reductase K05885; COG: COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); Psort location: Cytoplasmic, score: 8.87.
  
     0.411
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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