| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDR45822.1 | EDR46541.1 | DORFOR_02423 | DORFOR_01763 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 2.1e-42 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.36. | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | 0.623 |
| EDR45822.1 | EDR46694.1 | DORFOR_02423 | DORFOR_01917 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 2.1e-42 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.36. | Response regulator receiver domain protein; KEGG: ava:Ava_3369 1.5e-34 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.829 |
| EDR45822.1 | EDR48218.1 | DORFOR_02423 | DORFOR_00342 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 2.1e-42 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.36. | Hypothetical protein; KEGG: abo:ABO_0442 8.9e-07 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 8.87. | 0.882 |
| EDR45822.1 | EDR48417.1 | DORFOR_02423 | DORFOR_00159 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 2.1e-42 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.36. | Hypothetical protein. | 0.481 |
| EDR45822.1 | EDR48485.1 | DORFOR_02423 | DORFOR_00137 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 2.1e-42 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.36. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC00191 2.5e-55 sensory transduction histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.401 |
| EDR46541.1 | EDR45822.1 | DORFOR_01763 | DORFOR_02423 | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 2.1e-42 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.36. | 0.623 |
| EDR46541.1 | EDR46694.1 | DORFOR_01763 | DORFOR_01917 | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | Response regulator receiver domain protein; KEGG: ava:Ava_3369 1.5e-34 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.850 |
| EDR46541.1 | EDR46697.1 | DORFOR_01763 | DORFOR_01920 | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC00159 1.3e-35 sensory transduction protein kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.36. | 0.889 |
| EDR46541.1 | EDR46725.1 | DORFOR_01763 | DORFOR_01948 | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 3.5e-42 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.889 |
| EDR46541.1 | EDR47325.1 | DORFOR_01763 | DORFOR_01291 | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: sag:SAG1960 5.3e-62 sensor histidine kinase K02484; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.900 |
| EDR46541.1 | EDR48198.1 | DORFOR_01763 | DORFOR_00539 | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bca:BCE_2042 3.3e-53 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.922 |
| EDR46541.1 | EDR48218.1 | DORFOR_01763 | DORFOR_00342 | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; KEGG: abo:ABO_0442 8.9e-07 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 8.87. | 0.999 |
| EDR46541.1 | EDR48417.1 | DORFOR_01763 | DORFOR_00159 | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein. | 0.998 |
| EDR46541.1 | EDR48485.1 | DORFOR_01763 | DORFOR_00137 | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC00191 2.5e-55 sensory transduction histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.971 |
| EDR46541.1 | hemC | DORFOR_01763 | DORFOR_02964 | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.405 |
| EDR46694.1 | EDR45822.1 | DORFOR_01917 | DORFOR_02423 | Response regulator receiver domain protein; KEGG: ava:Ava_3369 1.5e-34 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 2.1e-42 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.36. | 0.829 |
| EDR46694.1 | EDR46541.1 | DORFOR_01917 | DORFOR_01763 | Response regulator receiver domain protein; KEGG: ava:Ava_3369 1.5e-34 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | 0.850 |
| EDR46694.1 | EDR46697.1 | DORFOR_01917 | DORFOR_01920 | Response regulator receiver domain protein; KEGG: ava:Ava_3369 1.5e-34 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC00159 1.3e-35 sensory transduction protein kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.36. | 0.933 |
| EDR46694.1 | EDR46725.1 | DORFOR_01917 | DORFOR_01948 | Response regulator receiver domain protein; KEGG: ava:Ava_3369 1.5e-34 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 3.5e-42 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.859 |
| EDR46694.1 | EDR47325.1 | DORFOR_01917 | DORFOR_01291 | Response regulator receiver domain protein; KEGG: ava:Ava_3369 1.5e-34 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: sag:SAG1960 5.3e-62 sensor histidine kinase K02484; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.809 |