Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDR46746.1COG: COG3066 DNA mismatch repair protein; Psort location: Cytoplasmic, score: 8.87. (219 aa)    
Predicted Functional Partners:
mutL
DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
   
 
 0.884
EDR46747.1
DNA-binding helix-turn-helix protein; Psort location: Cytoplasmic, score: 8.87.
       0.773
EDR46748.1
Hypothetical protein; KEGG: sth:STH2525 2.7e-05 type II restriction-modification system DNA methylase K07319; COG: COG0863 DNA modification methylase.
 
     0.506
dam
DNA adenine methylase; KEGG: smu:SMU.504 7.7e-54 dam; putative site-specific DNA-methyltransferase K06223; COG: COG0338 Site-specific DNA methylase.
 
   
 0.481
asnS
asparagine--tRNA ligase; KEGG: cno:NT01CX_1233 1.3e-179 asnS; asparaginyl-tRNA synthetase K01893; COG: COG0017 Aspartyl/asparaginyl-tRNA synthetases; Psort location: Cytoplasmic, score: 10.00.
  
     0.420
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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