| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDR46763.1 | EDR47321.1 | DORFOR_01986 | DORFOR_01287 | Hypothetical protein; COG: COG1609 Transcriptional regulators. | KEGG: spj:MGAS2096_Spy0983 0.0052 transcriptional regulator, GntR family / aminotransferase class-I; COG: COG1609 Transcriptional regulators. | 0.435 |
| EDR46763.1 | ccpA | DORFOR_01986 | DORFOR_01995 | Hypothetical protein; COG: COG1609 Transcriptional regulators. | Glucose-resistance amylase regulator; KEGG: efa:EF1922 8.1e-10 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; COG: COG1609 Transcriptional regulators; Psort location: Cytoplasmic, score: 9.98. | 0.491 |
| EDR46763.1 | guaA | DORFOR_01986 | DORFOR_01859 | Hypothetical protein; COG: COG1609 Transcriptional regulators. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.493 |
| EDR46763.1 | guaB | DORFOR_01986 | DORFOR_00900 | Hypothetical protein; COG: COG1609 Transcriptional regulators. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.493 |
| EDR46763.1 | pheT | DORFOR_01986 | DORFOR_02847 | Hypothetical protein; COG: COG1609 Transcriptional regulators. | KEGG: tte:TTE1688 1.9e-107 pheT; phenylalanyl-tRNA synthetase beta subunit K01890; COG: COG0073 EMAP domain; Psort location: Cytoplasmic, score: 9.98. | 0.451 |
| EDR46763.1 | ribB | DORFOR_01986 | DORFOR_00290 | Hypothetical protein; COG: COG1609 Transcriptional regulators. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.493 |
| EDR46775.1 | EDR46777.1 | DORFOR_01998 | DORFOR_02000 | Hypothetical protein; COG: NOG21159 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99. | Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. | 0.913 |
| EDR46775.1 | ccpA | DORFOR_01998 | DORFOR_01995 | Hypothetical protein; COG: NOG21159 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99. | Glucose-resistance amylase regulator; KEGG: efa:EF1922 8.1e-10 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; COG: COG1609 Transcriptional regulators; Psort location: Cytoplasmic, score: 9.98. | 0.542 |
| EDR46775.1 | dlgD | DORFOR_01998 | DORFOR_01996 | Hypothetical protein; COG: NOG21159 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99. | 3-dehydro-L-gulonate 2-dehydrogenase; KEGG: ecc:c4396 3.3e-78 yiaK; hypothetical oxidoreductase yiaK K08092; COG: COG2055 Malate/L-lactate dehydrogenases; Belongs to the LDH2/MDH2 oxidoreductase family. | 0.766 |
| EDR46777.1 | EDR46775.1 | DORFOR_02000 | DORFOR_01998 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; COG: NOG21159 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99. | 0.913 |
| EDR46777.1 | ccpA | DORFOR_02000 | DORFOR_01995 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. | Glucose-resistance amylase regulator; KEGG: efa:EF1922 8.1e-10 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; COG: COG1609 Transcriptional regulators; Psort location: Cytoplasmic, score: 9.98. | 0.565 |
| EDR46777.1 | dlgD | DORFOR_02000 | DORFOR_01996 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. | 3-dehydro-L-gulonate 2-dehydrogenase; KEGG: ecc:c4396 3.3e-78 yiaK; hypothetical oxidoreductase yiaK K08092; COG: COG2055 Malate/L-lactate dehydrogenases; Belongs to the LDH2/MDH2 oxidoreductase family. | 0.747 |
| EDR46813.1 | ccpA | DORFOR_02036 | DORFOR_01995 | UbiC transcription regulator-associated domain protein; KEGG: reh:H16_A3019 3.4e-11 hutC; histidine utilization repressor; COG: COG2188 Transcriptional regulators; Psort location: Cytoplasmic, score: 8.87. | Glucose-resistance amylase regulator; KEGG: efa:EF1922 8.1e-10 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; COG: COG1609 Transcriptional regulators; Psort location: Cytoplasmic, score: 9.98. | 0.491 |
| EDR46813.1 | guaA | DORFOR_02036 | DORFOR_01859 | UbiC transcription regulator-associated domain protein; KEGG: reh:H16_A3019 3.4e-11 hutC; histidine utilization repressor; COG: COG2188 Transcriptional regulators; Psort location: Cytoplasmic, score: 8.87. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.460 |
| EDR47321.1 | EDR46763.1 | DORFOR_01287 | DORFOR_01986 | KEGG: spj:MGAS2096_Spy0983 0.0052 transcriptional regulator, GntR family / aminotransferase class-I; COG: COG1609 Transcriptional regulators. | Hypothetical protein; COG: COG1609 Transcriptional regulators. | 0.435 |
| EDR47321.1 | ccpA | DORFOR_01287 | DORFOR_01995 | KEGG: spj:MGAS2096_Spy0983 0.0052 transcriptional regulator, GntR family / aminotransferase class-I; COG: COG1609 Transcriptional regulators. | Glucose-resistance amylase regulator; KEGG: efa:EF1922 8.1e-10 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; COG: COG1609 Transcriptional regulators; Psort location: Cytoplasmic, score: 9.98. | 0.573 |
| EDR47321.1 | guaA | DORFOR_01287 | DORFOR_01859 | KEGG: spj:MGAS2096_Spy0983 0.0052 transcriptional regulator, GntR family / aminotransferase class-I; COG: COG1609 Transcriptional regulators. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.493 |
| EDR47321.1 | guaB | DORFOR_01287 | DORFOR_00900 | KEGG: spj:MGAS2096_Spy0983 0.0052 transcriptional regulator, GntR family / aminotransferase class-I; COG: COG1609 Transcriptional regulators. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.493 |
| EDR47321.1 | pheT | DORFOR_01287 | DORFOR_02847 | KEGG: spj:MGAS2096_Spy0983 0.0052 transcriptional regulator, GntR family / aminotransferase class-I; COG: COG1609 Transcriptional regulators. | KEGG: tte:TTE1688 1.9e-107 pheT; phenylalanyl-tRNA synthetase beta subunit K01890; COG: COG0073 EMAP domain; Psort location: Cytoplasmic, score: 9.98. | 0.451 |
| EDR47321.1 | ribB | DORFOR_01287 | DORFOR_00290 | KEGG: spj:MGAS2096_Spy0983 0.0052 transcriptional regulator, GntR family / aminotransferase class-I; COG: COG1609 Transcriptional regulators. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.493 |