Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EDR46796.1Exonuclease; KEGG: psp:PSPPH_1792 4.5e-09 exonuclease; COG: COG5018 Inhibitor of the KinA pathway to sporulation, predicted exonuclease; Psort location: Cytoplasmic, score: 8.87. (218 aa)    
Predicted Functional Partners:
EDR46599.1
KEGG: tte:TTE1818 0. dnaE; DNA polymerase III alpha subunit K02337; COG: COG0587 DNA polymerase III, alpha subunit; Psort location: Cytoplasmic, score: 9.98.
   
 
 0.840
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 
 0.821
EDR46970.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
 
     0.759
holB
DNA polymerase III, delta' subunit; KEGG: tte:TTE0097 2.3e-52 holB; ATPase involved in DNA replication K02341; COG: COG2812 DNA polymerase III, gamma/tau subunits; Psort location: Cytoplasmic, score: 8.87.
    
 
 0.752
dnaX
DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
    
 
 0.752
holA
KEGG: bha:BH1337 3.6e-40 putative DNA polymerase III, delta subunit K02340; COG: COG1466 DNA polymerase III, delta subunit; Psort location: Cytoplasmic, score: 8.87.
    
 
 0.736
EDR47337.1
Von Willebrand factor type A domain protein; KEGG: cal:orf19.1648 0.00031 RAD50; DNA repair protein K01553; COG: COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain.
  
    0.632
rpmD
COG: COG1841 Ribosomal protein L30/L7E.
   
  0.612
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.595
EDR46350.1
Hypothetical protein; COG: COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily.
   
 
 0.593
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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