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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR46811.1Kinase, PfkB family; KEGG: ape:APE_0012 6.8e-23 ribokinase K00852; COG: COG0524 Sugar kinases, ribokinase family; Psort location: Cytoplasmic, score: 9.98; Belongs to the carbohydrate kinase PfkB family. (305 aa)    
Predicted Functional Partners:
EDR46810.1
ADP-ribosylglycohydrolase; KEGG: ser:SERP2218 2.3e-86 ADP-ribosylglycohydrolase, putative K05521; COG: COG1397 ADP-ribosylglycohydrolase; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.945
EDR45569.1
KEGG: cpr:CPR_0550 2.6e-163 fructose specific permease K00890; COG: COG1299 Phosphotransferase system, fructose-specific IIC component; Psort location: CytoplasmicMembrane, score: 10.00.
  
 
 0.889
pnuC
COG: COG3201 Nicotinamide mononucleotide transporter; Psort location: CytoplasmicMembrane, score: 9.99.
 
     0.888
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.794
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.780
EDR46324.1
AP endonuclease, family 2; KEGG: ret:RHE_PF00383 5.3e-07 putative epimerase protein K01820; COG: COG1082 Sugar phosphate isomerases/epimerases; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.738
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 
  0.687
EDR46626.1
Inosine-uridine preferring nucleoside hydrolase; KEGG: ecc:c0735 3.2e-71 ybeK; hypothetical protein YbeK K01250; COG: COG1957 Inosine-uridine nucleoside N-ribohydrolase; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.651
EDR46813.1
UbiC transcription regulator-associated domain protein; KEGG: reh:H16_A3019 3.4e-11 hutC; histidine utilization repressor; COG: COG2188 Transcriptional regulators; Psort location: Cytoplasmic, score: 8.87.
 
 
  0.648
EDR46627.1
KEGG: ava:Ava_3900 1.2e-23 inosine/uridine-preferring nucleoside hydrolase K01239; COG: COG1957 Inosine-uridine nucleoside N-ribohydrolase; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.630
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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