Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDR46811.1Kinase, PfkB family; KEGG: ape:APE_0012 6.8e-23 ribokinase K00852; COG: COG0524 Sugar kinases, ribokinase family; Psort location: Cytoplasmic, score: 9.98; Belongs to the carbohydrate kinase PfkB family. (305 aa)    
Predicted Functional Partners:
EDR46810.1
ADP-ribosylglycohydrolase; KEGG: ser:SERP2218 2.3e-86 ADP-ribosylglycohydrolase, putative K05521; COG: COG1397 ADP-ribosylglycohydrolase; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.947
pnuC
COG: COG3201 Nicotinamide mononucleotide transporter; Psort location: CytoplasmicMembrane, score: 9.99.
 
     0.888
EDR46813.1
UbiC transcription regulator-associated domain protein; KEGG: reh:H16_A3019 3.4e-11 hutC; histidine utilization repressor; COG: COG2188 Transcriptional regulators; Psort location: Cytoplasmic, score: 8.87.
 
     0.638
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
    0.626
EDR46626.1
Inosine-uridine preferring nucleoside hydrolase; KEGG: ecc:c0735 3.2e-71 ybeK; hypothetical protein YbeK K01250; COG: COG1957 Inosine-uridine nucleoside N-ribohydrolase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.586
EDR46627.1
KEGG: ava:Ava_3900 1.2e-23 inosine/uridine-preferring nucleoside hydrolase K01239; COG: COG1957 Inosine-uridine nucleoside N-ribohydrolase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.561
hisA
KEGG: ath:At2g36230 1.7e-72 F2H17.16; N'-5'-phosphoribosyl-formimino-5-aminoimidazole-4- carboxamide ribonucleotide isomerase K01814; COG: KOG3055 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; Psort location: Cytoplasmic, score: 8.87; Belongs to the HisA/HisF family.
  
    0.511
EDR46814.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.481
EDR46809.1
COG: COG1966 Carbon starvation protein, predicted membrane protein; Psort location: CytoplasmicMembrane, score: 9.99.
  
    0.415
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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