STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR46819.1HDIG domain protein; COG: COG1418 Predicted HD superfamily hydrolase; Psort location: Cytoplasmic, score: 8.87. (171 aa)    
Predicted Functional Partners:
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
   
 0.942
folP
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
     0.894
folE
GTP cyclohydrolase I; KEGG: cpe:CPE1019 5.9e-63 mtrA; GTP cyclohydrolase K01495; COG: COG0302 GTP cyclohydrolase I; Psort location: Cytoplasmic, score: 8.87.
 
     0.863
folC-2
KEGG: mta:Moth_0533 2.9e-70 FolC bifunctional protein K01930; COG: COG0285 Folylpolyglutamate synthase; Psort location: Cytoplasmic, score: 8.87.
 
     0.811
EDR46822.1
Response regulator receiver domain protein; KEGG: chu:CHU_2895 4.1e-66 sensory box histidine kinase/response regulator; COG: COG2203 FOG: GAF domain; Psort location: Cytoplasmic, score: 9.36.
       0.579
EDR46816.1
Hypothetical protein; KEGG: ctc:CTC01157 1.2e-15 phosphoesterase; COG: COG3326 Predicted membrane protein; Psort location: CytoplasmicMembrane, score: 9.99.
       0.481
thrH
KEGG: hch:HCH_02661 1.1e-54 thrH; phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein K01079; COG: COG0560 Phosphoserine phosphatase; Psort location: Cytoplasmic, score: 8.87.
       0.477
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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