| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDR45618.1 | EDR46833.1 | DORFOR_02219 | DORFOR_02056 | Hypothetical protein; KEGG: ava:Ava_0183 2.2e-10 peptidase M23B K08259; COG: COG0791 Cell wall-associated hydrolases (invasion-associated proteins); Psort location: Extracellular, score: 9.95. | KEGG: bce:BC4687 2.2e-40 N-acetylmuramoyl-L-alanine amidase K01446; COG: COG0860 N-acetylmuramoyl-L-alanine amidase. | 0.413 |
| EDR45618.1 | EDR47573.1 | DORFOR_02219 | DORFOR_01100 | Hypothetical protein; KEGG: ava:Ava_0183 2.2e-10 peptidase M23B K08259; COG: COG0791 Cell wall-associated hydrolases (invasion-associated proteins); Psort location: Extracellular, score: 9.95. | KEGG: bsu:BG10825 9.7e-31 cwlC; N-acetylmuramoyl-L-alanine amidase, peptidoglycan hydrolase, LytC amidase family K01448; COG: COG0860 N-acetylmuramoyl-L-alanine amidase; Psort location: Cytoplasmic, score: 8.87. | 0.460 |
| EDR46193.1 | EDR46833.1 | DORFOR_02801 | DORFOR_02056 | Peptidase, S54 family; KEGG: eci:UTI89_C0653 3.5e-23 hypothetical protein; COG: COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid); Psort location: CytoplasmicMembrane, score: 9.99. | KEGG: bce:BC4687 2.2e-40 N-acetylmuramoyl-L-alanine amidase K01446; COG: COG0860 N-acetylmuramoyl-L-alanine amidase. | 0.811 |
| EDR46193.1 | EDR47573.1 | DORFOR_02801 | DORFOR_01100 | Peptidase, S54 family; KEGG: eci:UTI89_C0653 3.5e-23 hypothetical protein; COG: COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid); Psort location: CytoplasmicMembrane, score: 9.99. | KEGG: bsu:BG10825 9.7e-31 cwlC; N-acetylmuramoyl-L-alanine amidase, peptidoglycan hydrolase, LytC amidase family K01448; COG: COG0860 N-acetylmuramoyl-L-alanine amidase; Psort location: Cytoplasmic, score: 8.87. | 0.418 |
| EDR46833.1 | EDR45618.1 | DORFOR_02056 | DORFOR_02219 | KEGG: bce:BC4687 2.2e-40 N-acetylmuramoyl-L-alanine amidase K01446; COG: COG0860 N-acetylmuramoyl-L-alanine amidase. | Hypothetical protein; KEGG: ava:Ava_0183 2.2e-10 peptidase M23B K08259; COG: COG0791 Cell wall-associated hydrolases (invasion-associated proteins); Psort location: Extracellular, score: 9.95. | 0.413 |
| EDR46833.1 | EDR46193.1 | DORFOR_02056 | DORFOR_02801 | KEGG: bce:BC4687 2.2e-40 N-acetylmuramoyl-L-alanine amidase K01446; COG: COG0860 N-acetylmuramoyl-L-alanine amidase. | Peptidase, S54 family; KEGG: eci:UTI89_C0653 3.5e-23 hypothetical protein; COG: COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid); Psort location: CytoplasmicMembrane, score: 9.99. | 0.811 |
| EDR46833.1 | EDR46834.1 | DORFOR_02056 | DORFOR_02057 | KEGG: bce:BC4687 2.2e-40 N-acetylmuramoyl-L-alanine amidase K01446; COG: COG0860 N-acetylmuramoyl-L-alanine amidase. | Cof-like hydrolase; KEGG: spb:M28_Spy1372 4.9e-13 peptidyl-prolyl cis-trans isomerase K01802; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87. | 0.777 |
| EDR46833.1 | EDR46836.1 | DORFOR_02056 | DORFOR_02059 | KEGG: bce:BC4687 2.2e-40 N-acetylmuramoyl-L-alanine amidase K01446; COG: COG0860 N-acetylmuramoyl-L-alanine amidase. | Hypothetical protein; Psort location: Extracellular, score: 8.82. | 0.697 |
| EDR46833.1 | EDR46839.1 | DORFOR_02056 | DORFOR_02062 | KEGG: bce:BC4687 2.2e-40 N-acetylmuramoyl-L-alanine amidase K01446; COG: COG0860 N-acetylmuramoyl-L-alanine amidase. | HAD hydrolase, family IA, variant 3; KEGG: tte:TTE0802 7.1e-12 predicted phosphatase/phosphohexomutase K01838; COG: COG0637 Predicted phosphatase/phosphohexomutase; Psort location: Cytoplasmic, score: 8.87. | 0.446 |
| EDR46833.1 | EDR47573.1 | DORFOR_02056 | DORFOR_01100 | KEGG: bce:BC4687 2.2e-40 N-acetylmuramoyl-L-alanine amidase K01446; COG: COG0860 N-acetylmuramoyl-L-alanine amidase. | KEGG: bsu:BG10825 9.7e-31 cwlC; N-acetylmuramoyl-L-alanine amidase, peptidoglycan hydrolase, LytC amidase family K01448; COG: COG0860 N-acetylmuramoyl-L-alanine amidase; Psort location: Cytoplasmic, score: 8.87. | 0.543 |
| EDR46833.1 | greA-2 | DORFOR_02056 | DORFOR_02058 | KEGG: bce:BC4687 2.2e-40 N-acetylmuramoyl-L-alanine amidase K01446; COG: COG0860 N-acetylmuramoyl-L-alanine amidase. | Prokaryotic transcription elongation factor, GreA/GreB domain protein; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. | 0.714 |
| EDR46833.1 | murE | DORFOR_02056 | DORFOR_02436 | KEGG: bce:BC4687 2.2e-40 N-acetylmuramoyl-L-alanine amidase K01446; COG: COG0860 N-acetylmuramoyl-L-alanine amidase. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.435 |
| EDR46833.1 | thiE | DORFOR_02056 | DORFOR_02061 | KEGG: bce:BC4687 2.2e-40 N-acetylmuramoyl-L-alanine amidase K01446; COG: COG0860 N-acetylmuramoyl-L-alanine amidase. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.446 |
| EDR46833.1 | thiM | DORFOR_02056 | DORFOR_02060 | KEGG: bce:BC4687 2.2e-40 N-acetylmuramoyl-L-alanine amidase K01446; COG: COG0860 N-acetylmuramoyl-L-alanine amidase. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.446 |
| EDR46834.1 | EDR46833.1 | DORFOR_02057 | DORFOR_02056 | Cof-like hydrolase; KEGG: spb:M28_Spy1372 4.9e-13 peptidyl-prolyl cis-trans isomerase K01802; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87. | KEGG: bce:BC4687 2.2e-40 N-acetylmuramoyl-L-alanine amidase K01446; COG: COG0860 N-acetylmuramoyl-L-alanine amidase. | 0.777 |
| EDR46834.1 | EDR46836.1 | DORFOR_02057 | DORFOR_02059 | Cof-like hydrolase; KEGG: spb:M28_Spy1372 4.9e-13 peptidyl-prolyl cis-trans isomerase K01802; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; Psort location: Extracellular, score: 8.82. | 0.732 |
| EDR46834.1 | EDR46839.1 | DORFOR_02057 | DORFOR_02062 | Cof-like hydrolase; KEGG: spb:M28_Spy1372 4.9e-13 peptidyl-prolyl cis-trans isomerase K01802; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87. | HAD hydrolase, family IA, variant 3; KEGG: tte:TTE0802 7.1e-12 predicted phosphatase/phosphohexomutase K01838; COG: COG0637 Predicted phosphatase/phosphohexomutase; Psort location: Cytoplasmic, score: 8.87. | 0.468 |
| EDR46834.1 | greA-2 | DORFOR_02057 | DORFOR_02058 | Cof-like hydrolase; KEGG: spb:M28_Spy1372 4.9e-13 peptidyl-prolyl cis-trans isomerase K01802; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87. | Prokaryotic transcription elongation factor, GreA/GreB domain protein; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. | 0.732 |
| EDR46834.1 | thiE | DORFOR_02057 | DORFOR_02061 | Cof-like hydrolase; KEGG: spb:M28_Spy1372 4.9e-13 peptidyl-prolyl cis-trans isomerase K01802; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.470 |
| EDR46834.1 | thiM | DORFOR_02057 | DORFOR_02060 | Cof-like hydrolase; KEGG: spb:M28_Spy1372 4.9e-13 peptidyl-prolyl cis-trans isomerase K01802; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.470 |