STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR46836.1Hypothetical protein; Psort location: Extracellular, score: 8.82. (52 aa)    
Predicted Functional Partners:
greA-2
Prokaryotic transcription elongation factor, GreA/GreB domain protein; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
       0.773
EDR46834.1
Cof-like hydrolase; KEGG: spb:M28_Spy1372 4.9e-13 peptidyl-prolyl cis-trans isomerase K01802; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87.
       0.732
EDR46833.1
KEGG: bce:BC4687 2.2e-40 N-acetylmuramoyl-L-alanine amidase K01446; COG: COG0860 N-acetylmuramoyl-L-alanine amidase.
       0.697
thiM
Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
       0.488
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
       0.488
EDR46839.1
HAD hydrolase, family IA, variant 3; KEGG: tte:TTE0802 7.1e-12 predicted phosphatase/phosphohexomutase K01838; COG: COG0637 Predicted phosphatase/phosphohexomutase; Psort location: Cytoplasmic, score: 8.87.
       0.488
thiD
KEGG: cac:CAC3095 3.4e-83 thiK; phosphomethylpyrimidine kinase K00877:K00941; COG: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
       0.446
cytX
Putative hydroxymethylpyrimidine transporter CytX; COG: COG1457 Purine-cytosine permease and related proteins; Psort location: CytoplasmicMembrane, score: 10.00.
       0.426
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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