| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDR45356.1 | cytX | DORFOR_03140 | DORFOR_02064 | Putative thiamine-phosphate diphosphorylase; KEGG: ctc:CTC01746 9.6e-24 tenI; regulatory protein tenI K00788; COG: COG0352 Thiamine monophosphate synthase; Psort location: Cytoplasmic, score: 8.87. | Putative hydroxymethylpyrimidine transporter CytX; COG: COG1457 Purine-cytosine permease and related proteins; Psort location: CytoplasmicMembrane, score: 10.00. | 0.417 |
| EDR45356.1 | thiC | DORFOR_03140 | DORFOR_01676 | Putative thiamine-phosphate diphosphorylase; KEGG: ctc:CTC01746 9.6e-24 tenI; regulatory protein tenI K00788; COG: COG0352 Thiamine monophosphate synthase; Psort location: Cytoplasmic, score: 8.87. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.847 |
| EDR45356.1 | thiD | DORFOR_03140 | DORFOR_02063 | Putative thiamine-phosphate diphosphorylase; KEGG: ctc:CTC01746 9.6e-24 tenI; regulatory protein tenI K00788; COG: COG0352 Thiamine monophosphate synthase; Psort location: Cytoplasmic, score: 8.87. | KEGG: cac:CAC3095 3.4e-83 thiK; phosphomethylpyrimidine kinase K00877:K00941; COG: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.960 |
| EDR45356.1 | thiG | DORFOR_03140 | DORFOR_02214 | Putative thiamine-phosphate diphosphorylase; KEGG: ctc:CTC01746 9.6e-24 tenI; regulatory protein tenI K00788; COG: COG0352 Thiamine monophosphate synthase; Psort location: Cytoplasmic, score: 8.87. | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.909 |
| EDR45356.1 | thiH | DORFOR_03140 | DORFOR_02213 | Putative thiamine-phosphate diphosphorylase; KEGG: ctc:CTC01746 9.6e-24 tenI; regulatory protein tenI K00788; COG: COG0352 Thiamine monophosphate synthase; Psort location: Cytoplasmic, score: 8.87. | Thiazole biosynthesis protein ThiH; KEGG: mac:MA0154 1.6e-14 bioB; biotin synthase K01012; COG: COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes; Psort location: Cytoplasmic, score: 8.87. | 0.938 |
| EDR45356.1 | thiM | DORFOR_03140 | DORFOR_02060 | Putative thiamine-phosphate diphosphorylase; KEGG: ctc:CTC01746 9.6e-24 tenI; regulatory protein tenI K00788; COG: COG0352 Thiamine monophosphate synthase; Psort location: Cytoplasmic, score: 8.87. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.952 |
| EDR45356.1 | thiS | DORFOR_03140 | DORFOR_02215 | Putative thiamine-phosphate diphosphorylase; KEGG: ctc:CTC01746 9.6e-24 tenI; regulatory protein tenI K00788; COG: COG0352 Thiamine monophosphate synthase; Psort location: Cytoplasmic, score: 8.87. | COG: COG2104 Sulfur transfer protein involved in thiamine biosynthesis; Psort location: Cytoplasmic, score: 8.87. | 0.970 |
| EDR46839.1 | cytX | DORFOR_02062 | DORFOR_02064 | HAD hydrolase, family IA, variant 3; KEGG: tte:TTE0802 7.1e-12 predicted phosphatase/phosphohexomutase K01838; COG: COG0637 Predicted phosphatase/phosphohexomutase; Psort location: Cytoplasmic, score: 8.87. | Putative hydroxymethylpyrimidine transporter CytX; COG: COG1457 Purine-cytosine permease and related proteins; Psort location: CytoplasmicMembrane, score: 10.00. | 0.690 |
| EDR46839.1 | thiD | DORFOR_02062 | DORFOR_02063 | HAD hydrolase, family IA, variant 3; KEGG: tte:TTE0802 7.1e-12 predicted phosphatase/phosphohexomutase K01838; COG: COG0637 Predicted phosphatase/phosphohexomutase; Psort location: Cytoplasmic, score: 8.87. | KEGG: cac:CAC3095 3.4e-83 thiK; phosphomethylpyrimidine kinase K00877:K00941; COG: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.902 |
| EDR46839.1 | thiE | DORFOR_02062 | DORFOR_02061 | HAD hydrolase, family IA, variant 3; KEGG: tte:TTE0802 7.1e-12 predicted phosphatase/phosphohexomutase K01838; COG: COG0637 Predicted phosphatase/phosphohexomutase; Psort location: Cytoplasmic, score: 8.87. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.926 |
| EDR46839.1 | thiM | DORFOR_02062 | DORFOR_02060 | HAD hydrolase, family IA, variant 3; KEGG: tte:TTE0802 7.1e-12 predicted phosphatase/phosphohexomutase K01838; COG: COG0637 Predicted phosphatase/phosphohexomutase; Psort location: Cytoplasmic, score: 8.87. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.827 |
| EDR46931.1 | thiM | DORFOR_01421 | DORFOR_02060 | Hydrolase, NUDIX family; KEGG: tte:TTE1310 1.3e-33 mutT2; NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515; COG: COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Psort location: Cytoplasmic, score: 8.87. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.900 |
| cytX | EDR45356.1 | DORFOR_02064 | DORFOR_03140 | Putative hydroxymethylpyrimidine transporter CytX; COG: COG1457 Purine-cytosine permease and related proteins; Psort location: CytoplasmicMembrane, score: 10.00. | Putative thiamine-phosphate diphosphorylase; KEGG: ctc:CTC01746 9.6e-24 tenI; regulatory protein tenI K00788; COG: COG0352 Thiamine monophosphate synthase; Psort location: Cytoplasmic, score: 8.87. | 0.417 |
| cytX | EDR46839.1 | DORFOR_02064 | DORFOR_02062 | Putative hydroxymethylpyrimidine transporter CytX; COG: COG1457 Purine-cytosine permease and related proteins; Psort location: CytoplasmicMembrane, score: 10.00. | HAD hydrolase, family IA, variant 3; KEGG: tte:TTE0802 7.1e-12 predicted phosphatase/phosphohexomutase K01838; COG: COG0637 Predicted phosphatase/phosphohexomutase; Psort location: Cytoplasmic, score: 8.87. | 0.690 |
| cytX | thiD | DORFOR_02064 | DORFOR_02063 | Putative hydroxymethylpyrimidine transporter CytX; COG: COG1457 Purine-cytosine permease and related proteins; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: cac:CAC3095 3.4e-83 thiK; phosphomethylpyrimidine kinase K00877:K00941; COG: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.885 |
| cytX | thiE | DORFOR_02064 | DORFOR_02061 | Putative hydroxymethylpyrimidine transporter CytX; COG: COG1457 Purine-cytosine permease and related proteins; Psort location: CytoplasmicMembrane, score: 10.00. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.826 |
| cytX | thiM | DORFOR_02064 | DORFOR_02060 | Putative hydroxymethylpyrimidine transporter CytX; COG: COG1457 Purine-cytosine permease and related proteins; Psort location: CytoplasmicMembrane, score: 10.00. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.878 |
| thiC | EDR45356.1 | DORFOR_01676 | DORFOR_03140 | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | Putative thiamine-phosphate diphosphorylase; KEGG: ctc:CTC01746 9.6e-24 tenI; regulatory protein tenI K00788; COG: COG0352 Thiamine monophosphate synthase; Psort location: Cytoplasmic, score: 8.87. | 0.847 |
| thiC | thiD | DORFOR_01676 | DORFOR_02063 | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | KEGG: cac:CAC3095 3.4e-83 thiK; phosphomethylpyrimidine kinase K00877:K00941; COG: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.988 |
| thiC | thiE | DORFOR_01676 | DORFOR_02061 | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.957 |