STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR46886.1Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. (317 aa)    
Predicted Functional Partners:
mutL
DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
  
 0.997
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 0.993
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.993
EDR46885.1
Hypothetical protein.
 
     0.950
EDR46887.1
Hypothetical protein; COG: NOG17367 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
     0.948
EDR46884.1
Hypothetical protein; ORF located using Blastx.
 
     0.930
EDR46891.1
Hypothetical protein; KEGG: nme:NMB0700 8.8e-10 IgA-specific serine endopeptidase K01347; COG: COG0791 Cell wall-associated hydrolases (invasion-associated proteins).
 
     0.797
EDR46889.1
Hypothetical protein; COG: NOG36404 non supervised orthologous group.
 
     0.786
EDR46890.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
 
     0.783
EDR46882.1
Relaxase/mobilization nuclease domain protein; COG: COG3843 Type IV secretory pathway, VirD2 components (relaxase).
  
 
   0.745
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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