STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR46888.1DNA topoisomerase; KEGG: efa:EF2312 4.7e-189 topB-2; DNA topoisomerase III K03169; COG: COG0550 Topoisomerase IA; Psort location: Cytoplasmic, score: 8.87. (696 aa)    
Predicted Functional Partners:
EDR45655.1
Topoisomerase DNA-binding C4 zinc finger domain protein; KEGG: pab:PAB1430 5.2e-06 topA; DNA topoisomerase I K03168; COG: COG0514 Superfamily II DNA helicase; Psort location: Cytoplasmic, score: 8.87.
   
 0.971
nifJ
KEGG: ctc:CTC01741 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
  
   0.908
EDR46889.1
Hypothetical protein; COG: NOG36404 non supervised orthologous group.
 
     0.681
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 0.661
EDR46887.1
Hypothetical protein; COG: NOG17367 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
     0.659
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.649
EDR46890.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
 
     0.618
EDR46886.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
 
 
 
 0.613
EDR46891.1
Hypothetical protein; KEGG: nme:NMB0700 8.8e-10 IgA-specific serine endopeptidase K01347; COG: COG0791 Cell wall-associated hydrolases (invasion-associated proteins).
 
     0.575
EDR46885.1
Hypothetical protein.
 
     0.563
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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