STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
EDR45621.1Formiminotransferase-cyclodeaminase; KEGG: chy:CHY_1879 6.0e-47 fchA2; methenyltetrahydrofolate cyclohydrolase K01491; COG: COG3404 Methenyl tetrahydrofolate cyclohydrolase; Psort location: Cytoplasmic, score: 8.87. (244 aa)    
Predicted Functional Partners:
folD
Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.987
fhs
KEGG: spy:SPy2085 4.5e-207 fhs.2; formate--tetrahydrofolate ligase K01938; COG: COG2759 Formyltetrahydrofolate synthetase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.950
EDR45943.1
AICARFT/IMPCHase bienzyme; KEGG: dme:Dmel_CG11089 3.3e-124 CG11089 K00602:K01492; COG: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); Psort location: Cytoplasmic, score: 8.87.
 
  
  0.914
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
  
 
  0.912
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
     
  0.900
EDR45622.1
ABC transporter, ATP-binding protein; KEGG: cch:Cag_1482 4.2e-85 ATPase K06147; COG: COG1132 ABC-type multidrug transport system, ATPase and permease components; Psort location: CytoplasmicMembrane, score: 10.00.
  
    0.638
EDR48330.1
Aminotransferase, class V; KEGG: bsu:BG13993 2.1e-124 yurG; putative aminotransferase K00839; COG: COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.444
trpS
tryptophan--tRNA ligase; KEGG: bfs:BF3809 4.6e-143 trpS; tryptophanyl-tRNA synthetase K01867; COG: COG0180 Tryptophanyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.98; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.431
EDR48544.1
KEGG: ctc:CTC01806 6.6e-199 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; COG: COG1410 Methionine synthase I, cobalamin-binding domain; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.414
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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