| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDR45624.1 | EDR45626.1 | DORFOR_02225 | DORFOR_02227 | Putative chaperone protein DnaJ; KEGG: cme:CMJ043C 7.6e-09 phycocyanobilin lyase alpha subunit K02288; COG: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; Psort location: Cytoplasmic, score: 9.65. | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | 0.402 |
| EDR45624.1 | EDR45628.1 | DORFOR_02225 | DORFOR_02229 | Putative chaperone protein DnaJ; KEGG: cme:CMJ043C 7.6e-09 phycocyanobilin lyase alpha subunit K02288; COG: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; Psort location: Cytoplasmic, score: 9.65. | PAP2 family protein; KEGG: eci:UTI89_C1633 6.3e-05 ynbD; putative enzyme YnbD K01104; COG: COG0671 Membrane-associated phospholipid phosphatase; Psort location: CytoplasmicMembrane, score: 9.26. | 0.434 |
| EDR45624.1 | EDR47863.1 | DORFOR_02225 | DORFOR_00946 | Putative chaperone protein DnaJ; KEGG: cme:CMJ043C 7.6e-09 phycocyanobilin lyase alpha subunit K02288; COG: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; Psort location: Cytoplasmic, score: 9.65. | Methyltransferase domain protein; KEGG: btk:BT9727_3407 2.9e-16 possible ubiquinone/menaquinone methyltransferase K00599; COG: COG0500 SAM-dependent methyltransferases; Psort location: Cytoplasmic, score: 8.87. | 0.637 |
| EDR45624.1 | psd | DORFOR_02225 | DORFOR_02226 | Putative chaperone protein DnaJ; KEGG: cme:CMJ043C 7.6e-09 phycocyanobilin lyase alpha subunit K02288; COG: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; Psort location: Cytoplasmic, score: 9.65. | KEGG: cac:CAC0799 4.1e-55 psd; phosphatidylserine decarboxylase K01613; COG: COG0688 Phosphatidylserine decarboxylase; Belongs to the phosphatidylserine decarboxylase family. | 0.572 |
| EDR45626.1 | EDR45624.1 | DORFOR_02227 | DORFOR_02225 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | Putative chaperone protein DnaJ; KEGG: cme:CMJ043C 7.6e-09 phycocyanobilin lyase alpha subunit K02288; COG: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; Psort location: Cytoplasmic, score: 9.65. | 0.402 |
| EDR45626.1 | EDR45628.1 | DORFOR_02227 | DORFOR_02229 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | PAP2 family protein; KEGG: eci:UTI89_C1633 6.3e-05 ynbD; putative enzyme YnbD K01104; COG: COG0671 Membrane-associated phospholipid phosphatase; Psort location: CytoplasmicMembrane, score: 9.26. | 0.891 |
| EDR45626.1 | EDR45996.1 | DORFOR_02227 | DORFOR_02603 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | Acyltransferase; KEGG: oih:OB0869 3.8e-29 1-acyl-sn-glycerol-3-phosphate acetyltransferase K00655; COG: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; Psort location: Cytoplasmic, score: 8.87. | 0.631 |
| EDR45626.1 | EDR46393.1 | DORFOR_02227 | DORFOR_03005 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | Putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; KEGG: cac:CAC3596 3.8e-20 pgsA; phosphatidylglycerophosphate synthase K00995; COG: COG0558 Phosphatidylglycerophosphate synthase; Psort location: CytoplasmicMembrane, score: 9.75; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.894 |
| EDR45626.1 | EDR47250.1 | DORFOR_02227 | DORFOR_01742 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | Phospholipase D domain protein; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | 0.404 |
| EDR45626.1 | EDR47863.1 | DORFOR_02227 | DORFOR_00946 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | Methyltransferase domain protein; KEGG: btk:BT9727_3407 2.9e-16 possible ubiquinone/menaquinone methyltransferase K00599; COG: COG0500 SAM-dependent methyltransferases; Psort location: Cytoplasmic, score: 8.87. | 0.414 |
| EDR45626.1 | mprF | DORFOR_02227 | DORFOR_02228 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.883 |
| EDR45626.1 | pgsA | DORFOR_02227 | DORFOR_00578 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; KEGG: tte:TTE1376 6.5e-41 pgsA2; Phosphatidylglycerophosphate synthase K00995; COG: COG0558 Phosphatidylglycerophosphate synthase; Psort location: CytoplasmicMembrane, score: 9.26; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.893 |
| EDR45626.1 | psd | DORFOR_02227 | DORFOR_02226 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | KEGG: cac:CAC0799 4.1e-55 psd; phosphatidylserine decarboxylase K01613; COG: COG0688 Phosphatidylserine decarboxylase; Belongs to the phosphatidylserine decarboxylase family. | 0.991 |
| EDR45628.1 | EDR45624.1 | DORFOR_02229 | DORFOR_02225 | PAP2 family protein; KEGG: eci:UTI89_C1633 6.3e-05 ynbD; putative enzyme YnbD K01104; COG: COG0671 Membrane-associated phospholipid phosphatase; Psort location: CytoplasmicMembrane, score: 9.26. | Putative chaperone protein DnaJ; KEGG: cme:CMJ043C 7.6e-09 phycocyanobilin lyase alpha subunit K02288; COG: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; Psort location: Cytoplasmic, score: 9.65. | 0.434 |
| EDR45628.1 | EDR45626.1 | DORFOR_02229 | DORFOR_02227 | PAP2 family protein; KEGG: eci:UTI89_C1633 6.3e-05 ynbD; putative enzyme YnbD K01104; COG: COG0671 Membrane-associated phospholipid phosphatase; Psort location: CytoplasmicMembrane, score: 9.26. | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | 0.891 |
| EDR45628.1 | EDR47863.1 | DORFOR_02229 | DORFOR_00946 | PAP2 family protein; KEGG: eci:UTI89_C1633 6.3e-05 ynbD; putative enzyme YnbD K01104; COG: COG0671 Membrane-associated phospholipid phosphatase; Psort location: CytoplasmicMembrane, score: 9.26. | Methyltransferase domain protein; KEGG: btk:BT9727_3407 2.9e-16 possible ubiquinone/menaquinone methyltransferase K00599; COG: COG0500 SAM-dependent methyltransferases; Psort location: Cytoplasmic, score: 8.87. | 0.491 |
| EDR45628.1 | mprF | DORFOR_02229 | DORFOR_02228 | PAP2 family protein; KEGG: eci:UTI89_C1633 6.3e-05 ynbD; putative enzyme YnbD K01104; COG: COG0671 Membrane-associated phospholipid phosphatase; Psort location: CytoplasmicMembrane, score: 9.26. | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.908 |
| EDR45628.1 | psd | DORFOR_02229 | DORFOR_02226 | PAP2 family protein; KEGG: eci:UTI89_C1633 6.3e-05 ynbD; putative enzyme YnbD K01104; COG: COG0671 Membrane-associated phospholipid phosphatase; Psort location: CytoplasmicMembrane, score: 9.26. | KEGG: cac:CAC0799 4.1e-55 psd; phosphatidylserine decarboxylase K01613; COG: COG0688 Phosphatidylserine decarboxylase; Belongs to the phosphatidylserine decarboxylase family. | 0.847 |
| EDR45996.1 | EDR45626.1 | DORFOR_02603 | DORFOR_02227 | Acyltransferase; KEGG: oih:OB0869 3.8e-29 1-acyl-sn-glycerol-3-phosphate acetyltransferase K00655; COG: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; Psort location: Cytoplasmic, score: 8.87. | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | 0.631 |
| EDR45996.1 | EDR46393.1 | DORFOR_02603 | DORFOR_03005 | Acyltransferase; KEGG: oih:OB0869 3.8e-29 1-acyl-sn-glycerol-3-phosphate acetyltransferase K00655; COG: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; Psort location: Cytoplasmic, score: 8.87. | Putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; KEGG: cac:CAC3596 3.8e-20 pgsA; phosphatidylglycerophosphate synthase K00995; COG: COG0558 Phosphatidylglycerophosphate synthase; Psort location: CytoplasmicMembrane, score: 9.75; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.409 |