| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDR45626.1 | EDR45628.1 | DORFOR_02227 | DORFOR_02229 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | PAP2 family protein; KEGG: eci:UTI89_C1633 6.3e-05 ynbD; putative enzyme YnbD K01104; COG: COG0671 Membrane-associated phospholipid phosphatase; Psort location: CytoplasmicMembrane, score: 9.26. | 0.891 |
| EDR45626.1 | EDR45996.1 | DORFOR_02227 | DORFOR_02603 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | Acyltransferase; KEGG: oih:OB0869 3.8e-29 1-acyl-sn-glycerol-3-phosphate acetyltransferase K00655; COG: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; Psort location: Cytoplasmic, score: 8.87. | 0.631 |
| EDR45626.1 | EDR46393.1 | DORFOR_02227 | DORFOR_03005 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | Putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; KEGG: cac:CAC3596 3.8e-20 pgsA; phosphatidylglycerophosphate synthase K00995; COG: COG0558 Phosphatidylglycerophosphate synthase; Psort location: CytoplasmicMembrane, score: 9.75; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.894 |
| EDR45626.1 | cdsA | DORFOR_02227 | DORFOR_00683 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | KEGG: ctc:CTC01266 9.7e-47 phosphatidate cytidylyltransferase K00981; COG: COG0575 CDP-diglyceride synthetase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDS family. | 0.892 |
| EDR45626.1 | cysE | DORFOR_02227 | DORFOR_00766 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | KEGG: chy:CHY_2339 6.4e-66 cysE; serine acetyltransferase K00640; COG: COG1045 Serine acetyltransferase; Psort location: Cytoplasmic, score: 9.98. | 0.850 |
| EDR45626.1 | ilvA | DORFOR_02227 | DORFOR_01477 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | KEGG: fnu:FN1411 1.5e-114 threonine dehydratase K01754; COG: COG1171 Threonine dehydratase. | 0.850 |
| EDR45626.1 | mprF | DORFOR_02227 | DORFOR_02228 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.883 |
| EDR45626.1 | pgsA | DORFOR_02227 | DORFOR_00578 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; KEGG: tte:TTE1376 6.5e-41 pgsA2; Phosphatidylglycerophosphate synthase K00995; COG: COG0558 Phosphatidylglycerophosphate synthase; Psort location: CytoplasmicMembrane, score: 9.26; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.893 |
| EDR45626.1 | psd | DORFOR_02227 | DORFOR_02226 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | KEGG: cac:CAC0799 4.1e-55 psd; phosphatidylserine decarboxylase K01613; COG: COG0688 Phosphatidylserine decarboxylase; Belongs to the phosphatidylserine decarboxylase family. | 0.991 |
| EDR45626.1 | thrH | DORFOR_02227 | DORFOR_02046 | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | KEGG: hch:HCH_02661 1.1e-54 thrH; phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein K01079; COG: COG0560 Phosphoserine phosphatase; Psort location: Cytoplasmic, score: 8.87. | 0.857 |
| EDR45628.1 | EDR45626.1 | DORFOR_02229 | DORFOR_02227 | PAP2 family protein; KEGG: eci:UTI89_C1633 6.3e-05 ynbD; putative enzyme YnbD K01104; COG: COG0671 Membrane-associated phospholipid phosphatase; Psort location: CytoplasmicMembrane, score: 9.26. | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | 0.891 |
| EDR45628.1 | mprF | DORFOR_02229 | DORFOR_02228 | PAP2 family protein; KEGG: eci:UTI89_C1633 6.3e-05 ynbD; putative enzyme YnbD K01104; COG: COG0671 Membrane-associated phospholipid phosphatase; Psort location: CytoplasmicMembrane, score: 9.26. | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.908 |
| EDR45628.1 | psd | DORFOR_02229 | DORFOR_02226 | PAP2 family protein; KEGG: eci:UTI89_C1633 6.3e-05 ynbD; putative enzyme YnbD K01104; COG: COG0671 Membrane-associated phospholipid phosphatase; Psort location: CytoplasmicMembrane, score: 9.26. | KEGG: cac:CAC0799 4.1e-55 psd; phosphatidylserine decarboxylase K01613; COG: COG0688 Phosphatidylserine decarboxylase; Belongs to the phosphatidylserine decarboxylase family. | 0.847 |
| EDR45996.1 | EDR45626.1 | DORFOR_02603 | DORFOR_02227 | Acyltransferase; KEGG: oih:OB0869 3.8e-29 1-acyl-sn-glycerol-3-phosphate acetyltransferase K00655; COG: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; Psort location: Cytoplasmic, score: 8.87. | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | 0.631 |
| EDR45996.1 | EDR46393.1 | DORFOR_02603 | DORFOR_03005 | Acyltransferase; KEGG: oih:OB0869 3.8e-29 1-acyl-sn-glycerol-3-phosphate acetyltransferase K00655; COG: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; Psort location: Cytoplasmic, score: 8.87. | Putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; KEGG: cac:CAC3596 3.8e-20 pgsA; phosphatidylglycerophosphate synthase K00995; COG: COG0558 Phosphatidylglycerophosphate synthase; Psort location: CytoplasmicMembrane, score: 9.75; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.409 |
| EDR45996.1 | cdsA | DORFOR_02603 | DORFOR_00683 | Acyltransferase; KEGG: oih:OB0869 3.8e-29 1-acyl-sn-glycerol-3-phosphate acetyltransferase K00655; COG: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; Psort location: Cytoplasmic, score: 8.87. | KEGG: ctc:CTC01266 9.7e-47 phosphatidate cytidylyltransferase K00981; COG: COG0575 CDP-diglyceride synthetase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDS family. | 0.944 |
| EDR45996.1 | pgsA | DORFOR_02603 | DORFOR_00578 | Acyltransferase; KEGG: oih:OB0869 3.8e-29 1-acyl-sn-glycerol-3-phosphate acetyltransferase K00655; COG: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; Psort location: Cytoplasmic, score: 8.87. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; KEGG: tte:TTE1376 6.5e-41 pgsA2; Phosphatidylglycerophosphate synthase K00995; COG: COG0558 Phosphatidylglycerophosphate synthase; Psort location: CytoplasmicMembrane, score: 9.26; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.409 |
| EDR45996.1 | psd | DORFOR_02603 | DORFOR_02226 | Acyltransferase; KEGG: oih:OB0869 3.8e-29 1-acyl-sn-glycerol-3-phosphate acetyltransferase K00655; COG: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; Psort location: Cytoplasmic, score: 8.87. | KEGG: cac:CAC0799 4.1e-55 psd; phosphatidylserine decarboxylase K01613; COG: COG0688 Phosphatidylserine decarboxylase; Belongs to the phosphatidylserine decarboxylase family. | 0.508 |
| EDR46393.1 | EDR45626.1 | DORFOR_03005 | DORFOR_02227 | Putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; KEGG: cac:CAC3596 3.8e-20 pgsA; phosphatidylglycerophosphate synthase K00995; COG: COG0558 Phosphatidylglycerophosphate synthase; Psort location: CytoplasmicMembrane, score: 9.75; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99. | 0.894 |
| EDR46393.1 | EDR45996.1 | DORFOR_03005 | DORFOR_02603 | Putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; KEGG: cac:CAC3596 3.8e-20 pgsA; phosphatidylglycerophosphate synthase K00995; COG: COG0558 Phosphatidylglycerophosphate synthase; Psort location: CytoplasmicMembrane, score: 9.75; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Acyltransferase; KEGG: oih:OB0869 3.8e-29 1-acyl-sn-glycerol-3-phosphate acetyltransferase K00655; COG: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; Psort location: Cytoplasmic, score: 8.87. | 0.409 |