Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mprFHypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. (343 aa)    
Predicted Functional Partners:
EDR45628.1
PAP2 family protein; KEGG: eci:UTI89_C1633 6.3e-05 ynbD; putative enzyme YnbD K01104; COG: COG0671 Membrane-associated phospholipid phosphatase; Psort location: CytoplasmicMembrane, score: 9.26.
 
     0.907
EDR45626.1
CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99.
 
  
 0.874
psd
KEGG: cac:CAC0799 4.1e-55 psd; phosphatidylserine decarboxylase K01613; COG: COG0688 Phosphatidylserine decarboxylase; Belongs to the phosphatidylserine decarboxylase family.
 
   
 0.764
EDR47484.1
Hypothetical protein; COG: NOG21901 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
     0.484
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.448
EDR47298.1
Hypothetical protein; KEGG: sec:SC1961 4.7e-11 fliB; N-methylation of lysine residues in flagellin K00599; COG: NOG18602 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
     0.448
EDR47950.1
Alcohol acetyltransferase; COG: NOG32388 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.97.
  
     0.437
EDR45629.1
Methionine synthase, vitamin-B12 independent; KEGG: lsl:LSL_0129 3.3e-69 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase K00549; COG: COG0620 Methionine synthase II (cobalamin-independent); Psort location: Cytoplasmic, score: 8.87.
       0.422
EDR45506.1
Hypothetical protein; COG: NOG13188 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
     0.410
EDR45649.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.404
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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