Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
EDR45628.1PAP2 family protein; KEGG: eci:UTI89_C1633 6.3e-05 ynbD; putative enzyme YnbD K01104; COG: COG0671 Membrane-associated phospholipid phosphatase; Psort location: CytoplasmicMembrane, score: 9.26. (259 aa)    
Predicted Functional Partners:
mprF
Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
 
     0.907
EDR45626.1
CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.0e-33 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.99.
 
   
 0.891
psd
KEGG: cac:CAC0799 4.1e-55 psd; phosphatidylserine decarboxylase K01613; COG: COG0688 Phosphatidylserine decarboxylase; Belongs to the phosphatidylserine decarboxylase family.
 
   
 0.840
EDR45525.1
NAD dependent epimerase/dehydratase family protein; KEGG: vfi:VF0192 9.7e-63 UDP-2-acetamido-2,6-dideoxy-beta-L-talose 4-dehydrogenase K00100; COG: COG0451 Nucleoside-diphosphate-sugar epimerases; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.674
EDR48227.1
Hypothetical protein; KEGG: lil:LA0051 0.0019 dTDPglucose 4,6-dehydratase K01710; COG: COG0451 Nucleoside-diphosphate-sugar epimerases; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.665
EDR48532.1
Polyprenyl synthetase; KEGG: cpf:CPF_2074 7.0e-60 ispA; geranyltranstransferase K00795; COG: COG0142 Geranylgeranyl pyrophosphate synthase; Psort location: Cytoplasmic, score: 9.98; Belongs to the FPP/GGPP synthase family.
  
 
 0.636
gap
Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: chu:CHU_2987 4.8e-100 gapA; glyceraldehyde-3-phosphate dehydrogenase A K00134; COG: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 9.98.
   
  
 0.549
gap-2
KEGG: fth:FTH_1121 3.4e-122 gapA; glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) K00134; COG: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 9.98.
   
  
 0.549
EDR45631.1
MATE efflux family protein; COG: COG0534 Na+-driven multidrug efflux pump; Psort location: CytoplasmicMembrane, score: 9.99.
  
    0.492
EDR48322.1
Hydrolase, NUDIX family; KEGG: fnu:FN1791 8.3e-41 mutator MutT protein K03574; COG: COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.479
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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