Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDR45683.14Fe-4S binding domain protein; KEGG: ecp:ECP_0909 5.9e-24 anaerobic dimethyl sulfoxide reductase, subunit B K07307; COG: COG0437 Fe-S-cluster-containing hydrogenase components 1; Psort location: CytoplasmicMembrane, score: 9.49. (142 aa)    
Predicted Functional Partners:
EDR45684.1
KEGG: afu:AF1203 7.7e-86 molybdopterin oxidoreductase, molybdopterin binding subunit K00183; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: Cytoplasmic, score: 8.87; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 0.987
EDR47154.1
KEGG: afu:AF1203 1.7e-74 molybdopterin oxidoreductase, molybdopterin binding subunit K00183; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: Cytoplasmic, score: 8.87; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 0.944
EDR45799.1
KEGG: afu:AF1203 1.6e-69 molybdopterin oxidoreductase, molybdopterin binding subunit K00183; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: Cytoplasmic, score: 8.87; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 0.929
tuf
Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
  
 
 0.819
EDR47155.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: tma:TM0395 2.2e-49 NADH oxidase, putative K00359; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: Cytoplasmic, score: 9.98.
 
 
 
 0.803
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
    0.704
EDR46752.1
COG: COG1715 Restriction endonuclease; Psort location: Cytoplasmic, score: 8.87.
   
    0.704
mobB
Molybdopterin-guanine dinucleotide biosynthesis protein B; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
 
     0.701
EDR47362.1
Molybdopterin oxidoreductase; KEGG: msu:MS0732 3.0e-203 uncharacterized anaerobic dehydrogenase K00123; COG: COG3383 Uncharacterized anaerobic dehydrogenase; Psort location: Cytoplasmic, score: 8.87; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
  
 0.674
EDR45682.1
Hypothetical protein.
       0.668
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.