Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDR45693.1Response regulator receiver domain protein; KEGG: rru:Rru_A0376 1.7e-17 transcriptional regulator, LytR/AlgR family K07705; COG: COG3279 Response regulator of the LytR/AlgR family; Psort location: Cytoplasmic, score: 8.87. (248 aa)    
Predicted Functional Partners:
EDR45694.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: gme:Gmet_2698 2.7e-67 histidine kinase internal region K07704; COG: COG3275 Putative regulator of cell autolysis; Psort location: CytoplasmicMembrane, score: 9.97.
 
 0.997
EDR47324.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC01848 5.7e-58 yesM; two-component sensor kinase YesM K07718; COG: COG2972 Predicted signal transduction protein with a C-terminal ATPase domain; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.856
EDR47036.1
HAMP domain protein; KEGG: bli:BL01744 5.2e-48 histidine kinase,histidine kinase, HAMP region; COG: COG2972 Predicted signal transduction protein with a C-terminal ATPase domain; Psort location: CytoplasmicMembrane, score: 9.98.
 
  
 0.811
EDR46784.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bha:BH3447 2.0e-64 two-component sensor histidine kinase K07718; COG: COG2972 Predicted signal transduction protein with a C-terminal ATPase domain.
 
  
 0.712
EDR48169.1
Hypothetical protein; KEGG: bcz:BCZK3376 8.5e-32 murein hydrolase export regulator K01238; COG: COG1346 Putative effector of murein hydrolase; Psort location: CytoplasmicMembrane, score: 9.99.
    
 0.662
EDR45695.1
Transporter, dicarboxylate/amino acid:cation Na+/H+ symporter family protein; KEGG: eci:UTI89_C4668 5.5e-44 gltP; glutamate-aspartate symport protein K03309; COG: COG1301 Na+/H+-dicarboxylate symporters; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
       0.509
EDR45697.1
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
  
  
 0.409
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.