STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR45697.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (305 aa)    
Predicted Functional Partners:
EDR45696.1
Hypothetical protein.
       0.773
EDR45695.1
Transporter, dicarboxylate/amino acid:cation Na+/H+ symporter family protein; KEGG: eci:UTI89_C4668 5.5e-44 gltP; glutamate-aspartate symport protein K03309; COG: COG1301 Na+/H+-dicarboxylate symporters; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
       0.584
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
    
 0.538
cobH
KEGG: ppd:Ppro_1269 5.4e-46 precorrin-8X methylmutase; COG: COG2082 Precorrin isomerase; Psort location: Cytoplasmic, score: 8.87.
       0.484
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
       0.484
EDR45700.1
Putative threonine-phosphate decarboxylase; KEGG: cpe:CPE1040 3.7e-77 probable Thr-phospho decarboxylase K00817; COG: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Psort location: Cytoplasmic, score: 8.87.
       0.484
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
  
 0.405
EDR45693.1
Response regulator receiver domain protein; KEGG: rru:Rru_A0376 1.7e-17 transcriptional regulator, LytR/AlgR family K07705; COG: COG3279 Response regulator of the LytR/AlgR family; Psort location: Cytoplasmic, score: 8.87.
  
    0.401
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.