Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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cobSCobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (272 aa)    
Predicted Functional Partners:
cobJ
precorrin-3B C(17)-methyltransferase; KEGG: lin:lin1162 4.3e-60 cbiH; similar to precorrin methylase K03395; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.979
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
 
 
 0.974
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.950
EDR45705.1
Hypothetical protein; KEGG: tde:TDE2382 1.1e-13 cobU; cobinamide kinase/cobinamide phosphate guanyltransferase K02231; COG: COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.944
EDR45703.1
Hypothetical protein; KEGG: cno:NT01CX_2078 3.1e-12 cobinamide kinase; COG: COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.926
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
   
 0.921
cobK
precorrin-6A reductase; KEGG: ctc:CTC00734 4.6e-56 cbiT; precorrin-6B methylase/decarboxylase cbiT/cbiE K03399:K02191; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.905
cobB
KEGG: lin:lin1154 2.8e-79 cbiA; similar to cobyrinic acid a,c-diamide synthase K03401; COG: COG1797 Cobyrinic acid a,c-diamide synthase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.902
EDR45702.1
Phosphoglycerate mutase family protein; KEGG: bha:BH1593 5.1e-25 alpha-ribazole-5'-phosphate phosphatase K02226; COG: COG0406 Fructose-2,6-bisphosphatase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.898
cobH
KEGG: ppd:Ppro_1269 5.4e-46 precorrin-8X methylmutase; COG: COG2082 Precorrin isomerase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.884
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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