Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EDR45742.1DNA-binding helix-turn-helix protein; KEGG: mmo:MMOB3450 0.00063 dam; adenine-specific DNA methyltransferase K06223; COG: COG1396 Predicted transcriptional regulators. (110 aa)    
Predicted Functional Partners:
EDR46848.1
Phage/plasmid primase, P4 family domain protein; KEGG: hwa:HQ4022A 3.5e-14 putative P4-specific DNA primase; COG: COG3378 Predicted ATPase; Psort location: Cytoplasmic, score: 8.87.
  
     0.706
EDR45404.1
Sigma-70, region 4; Psort location: Cytoplasmic, score: 8.87.
  
     0.587
EDR46767.1
DNA-binding helix-turn-helix protein; COG: NOG16841 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
     0.534
EDR45741.1
Repeat protein; COG: COG4886 Leucine-rich repeat (LRR) protein; Psort location: Cellwall, score: 10.00.
       0.503
EDR45740.1
Hypothetical protein; KEGG: ljo:LJ1840 6.8e-05 cell wall-associated serine proteinase K01361.
       0.479
EDR46766.1
DNA-binding helix-turn-helix protein; COG: COG1396 Predicted transcriptional regulators; Psort location: CytoplasmicMembrane, score: 9.26.
  
     0.438
EDR46047.1
Hypothetical protein; KEGG: wol:WD0969 0.00022 NADH dehydrogenase I, N subunit, putative K00343; COG: COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component; Psort location: CytoplasmicMembrane, score: 9.99.
  
     0.428
EDR47234.1
Plasmid stabilization system protein, RelE/ParE family.
  
     0.425
EDR46066.1
Hypothetical protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
  
     0.414
EDR47878.1
Glycosyltransferase, group 2 family protein; KEGG: hit:NTHI1474 1.7e-05 lgtD; UDP-glcNAc--lipooligosaccharide N-acetylglucosamine glycosyltransferase; COG: COG0463 Glycosyltransferases involved in cell wall biogenesis.
  
     0.407
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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