STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lepB-4KEGG: spb:M28_Spy0108 1.9e-18 signal peptidase I K03100; Belongs to the peptidase S26 family. (187 aa)    
Predicted Functional Partners:
EDR45802.1
Pilin isopeptide linkage domain protein; KEGG: ava:Ava_4160 0.0017 VCBS K01317.
 
     0.816
srtB-3
Sortase, SrtB family; COG: COG4509 Uncharacterized protein conserved in bacteria.
 
     0.814
EDR45805.1
Hypothetical protein.
       0.782
EDR45804.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.773
EDR47051.1
Putative cell division topological specificity factor MinE; Psort location: Cytoplasmic, score: 8.87.
   
    0.662
EDR45800.1
Pilin isopeptide linkage domain protein; Psort location: CytoplasmicMembrane, score: 9.75.
       0.615
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
  
 0.532
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
   
    0.509
phoU
Phosphate transport system regulatory protein PhoU; Plays a role in the regulation of phosphate uptake.
   
    0.509
lepB
Signal peptidase I; KEGG: mta:Moth_0972 1.2e-34 peptidase S26A, signal peptidase I K03100; COG: COG0681 Signal peptidase I; Psort location: CytoplasmicMembrane, score: 9.82.
 
  
 0.499
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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