STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR45823.1Response regulator receiver domain protein; KEGG: ava:Ava_1878 4.8e-29 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. (217 aa)    
Predicted Functional Partners:
EDR45822.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 2.1e-42 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.36.
 
  0.964
EDR48218.1
Hypothetical protein; KEGG: abo:ABO_0442 8.9e-07 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 8.87.
  
 0.908
EDR46541.1
Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87.
  
 0.850
EDR48485.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC00191 2.5e-55 sensory transduction histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
 0.811
EDR47325.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: sag:SAG1960 5.3e-62 sensor histidine kinase K02484; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
 
  0.807
EDR48417.1
Hypothetical protein.
  
 0.790
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
    
 0.783
cobA
uroporphyrinogen-III C-methyltransferase; KEGG: cno:NT01CX_0261 1.5e-89 uroporphyrinogen III synthase/methyltransferase K00589; COG: COG1587 Uroporphyrinogen-III synthase; Psort location: Cytoplasmic, score: 8.87.
    
 0.783
EDR45878.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bli:BL00395 1.1e-45 phoR; two-component sensor histidine kinase K07636; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.82.
 
  0.772
EDR46680.1
KEGG: eci:UTI89_C2354 1.3e-12 baeR; transcriptional response regulatory protein BaeR K07664; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
  
  
  0.742
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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