Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDR45877.1Hypothetical protein; COG: NOG21949 non supervised orthologous group. (305 aa)    
Predicted Functional Partners:
EDR45878.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bli:BL00395 1.1e-45 phoR; two-component sensor histidine kinase K07636; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.82.
 
    0.929
EDR45879.1
Response regulator receiver domain protein; KEGG: ava:Ava_1878 6.4e-50 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
     0.797
EDR45876.1
DNA internalization competence protein ComEC/Rec2-like protein; COG: COG0658 Predicted membrane metal-binding protein; Psort location: CytoplasmicMembrane, score: 9.97.
 
     0.788
EDR45880.1
comEA protein; COG: COG1555 DNA uptake protein and related DNA-binding proteins; Psort location: CytoplasmicMembrane, score: 9.49.
  
    0.776
holA
KEGG: bha:BH1337 3.6e-40 putative DNA polymerase III, delta subunit K02340; COG: COG1466 DNA polymerase III, delta subunit; Psort location: Cytoplasmic, score: 8.87.
 
     0.775
EDR46603.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.75.
  
     0.762
EDR47057.1
KEGG: lmf:LMOf2365_1848 0.0085 protein kinase, putative K08884.
 
     0.761
mreD
Rod shape-determining protein MreD; COG: NOG16883 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.
  
     0.753
EDR48260.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
     0.752
EDR48461.1
Small acid-soluble spore protein K family; Psort location: CytoplasmicMembrane, score: 9.99.
  
     0.745
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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