Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pyrFKEGG: blo:BL0791 4.1e-64 pyrF; orotidine 5'-phosphate decarboxylase K01591; COG: COG0284 Orotidine-5-phosphate decarboxylase; Psort location: Cytoplasmic, score: 8.87; Belongs to the OMP decarboxylase family. Type 2 subfamily. (308 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
 
 0.999
pyrD
Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate.
  
  
 0.981
pyrK
Oxidoreductase NAD-binding domain protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
  
  
 0.964
pyrB
KEGG: cac:CAC2654 8.0e-107 aspartate carbamoyltransferase catalytic subunit K00609; COG: COG0540 Aspartate carbamoyltransferase, catalytic chain; Psort location: Cytoplasmic, score: 9.98; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
 
  
 0.941
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.940
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.923
carB
KEGG: cpe:CPE2572 0. carB; carbamoyl-phosphate synthetase catalytic subunit K01955; COG: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Psort location: Cytoplasmic, score: 8.87.
 
  
 0.920
EDR47968.1
Phosphoribulokinase/uridine kinase family protein; KEGG: cpe:CPE1347 1.3e-122 probable uridine kinase K00876; COG: COG0572 Uridine kinase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.911
carA
KEGG: ldb:Ldb1070 1.2e-110 carA2a; carbamoyl-phosphate synthase small chain K01954; COG: COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family.
 
  
 0.904
maf
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
     
  0.900
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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