STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR45929.1Hypothetical protein; KEGG: afu:AF1311 3.1e-27 oxygen-independent coproporphyrinogen III oxidase, putative; COG: COG1032 Fe-S oxidoreductase; Psort location: Cytoplasmic, score: 8.87. (261 aa)    
Predicted Functional Partners:
EDR46806.1
Putative polyphosphate:AMP phosphotransferase; KEGG: ret:RHE_PC00203 1.5e-43 hypothetical protein K00937; COG: COG2326 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
   
    0.513
EDR45927.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bca:BCE_1587 5.3e-62 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase.
       0.476
EDR45928.1
Response regulator receiver domain protein; KEGG: ava:Ava_1878 8.1e-43 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
       0.476
hisH
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
       0.437
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
       0.420
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.