Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EDR45940.1Radical SAM domain protein; KEGG: mka:MK1086 0.00066 ferredoxin domain fused to pyruvate-formate lyase-activating enzyme K04069; COG: COG0535 Predicted Fe-S oxidoreductases; Psort location: Cytoplasmic, score: 8.87. (484 aa)    
Predicted Functional Partners:
EDR45941.1
Hypothetical protein; Probably functions as a manganese efflux pump.
       0.773
EDR45942.1
Hypothetical protein.
       0.516
EDR45939.1
Putative dihydroxyacetone kinase regulator; COG: COG1309 Transcriptional regulator; Psort location: Cytoplasmic, score: 8.87.
       0.495
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
  
  
 0.468
cobA
uroporphyrinogen-III C-methyltransferase; KEGG: cno:NT01CX_0261 1.5e-89 uroporphyrinogen III synthase/methyltransferase K00589; COG: COG1587 Uroporphyrinogen-III synthase; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.468
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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