STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR45944.1IMP cyclohydrolase-like protein; KEGG: mka:MK0087 1.5e-07 IMP cyclohydrolase K01492; COG: COG3363 Archaeal IMP cyclohydrolase; Psort location: Cytoplasmic, score: 8.87. (237 aa)    
Predicted Functional Partners:
EDR45943.1
AICARFT/IMPCHase bienzyme; KEGG: dme:Dmel_CG11089 3.3e-124 CG11089 K00602:K01492; COG: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); Psort location: Cytoplasmic, score: 8.87.
 
  
 0.993
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
   
  0.920
EDR47701.1
Phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 0. purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; COG: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.912
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.866
purD
KEGG: dps:DP2188 1.5e-114 probable phosphoribosylamine--glycine ligase K01945; COG: COG0151 Phosphoribosylamine-glycine ligase; Psort location: Cytoplasmic, score: 8.87; Belongs to the GARS family.
  
 
 0.562
EDR45744.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
     0.499
EDR45945.1
Hypothetical protein.
       0.479
EDR45727.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
     0.470
EDR47733.1
DRTGG domain protein; KEGG: ctc:CTC01649 2.0e-126 putative manganese-dependent inorganic pyrophosphatase K01507; COG: COG1227 Inorganic pyrophosphatase/exopolyphosphatase; Psort location: Cytoplasmic, score: 8.87.
  
  
  0.444
purC
KEGG: gsu:GSU2091 1.0e-83 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; COG: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Psort location: Cytoplasmic, score: 8.87; Belongs to the SAICAR synthetase family.
 
   
 0.443
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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