| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDR45943.1 | EDR45950.1 | DORFOR_02545 | DORFOR_02552 | AICARFT/IMPCHase bienzyme; KEGG: dme:Dmel_CG11089 3.3e-124 CG11089 K00602:K01492; COG: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); Psort location: Cytoplasmic, score: 8.87. | Oxidoreductase; COG: NOG16874 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | 0.484 |
| EDR45943.1 | EDR48544.1 | DORFOR_02545 | DORFOR_00090 | AICARFT/IMPCHase bienzyme; KEGG: dme:Dmel_CG11089 3.3e-124 CG11089 K00602:K01492; COG: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); Psort location: Cytoplasmic, score: 8.87. | KEGG: ctc:CTC01806 6.6e-199 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; COG: COG1410 Methionine synthase I, cobalamin-binding domain; Psort location: Cytoplasmic, score: 8.87. | 0.865 |
| EDR45943.1 | thyA | DORFOR_02545 | DORFOR_00834 | AICARFT/IMPCHase bienzyme; KEGG: dme:Dmel_CG11089 3.3e-124 CG11089 K00602:K01492; COG: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); Psort location: Cytoplasmic, score: 8.87. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.549 |
| EDR45948.1 | EDR45949.1 | DORFOR_02550 | DORFOR_02551 | Hypothetical protein; KEGG: cac:CAC0404 2.2e-09 serine/threonine protein kinase fused to TPR repeats domain K08884; COG: COG0515 Serine/threonine protein kinase; Psort location: Cytoplasmic, score: 8.87. | Radical SAM domain protein; COG: COG0535 Predicted Fe-S oxidoreductases; Psort location: Cytoplasmic, score: 8.87. | 0.445 |
| EDR45948.1 | EDR45950.1 | DORFOR_02550 | DORFOR_02552 | Hypothetical protein; KEGG: cac:CAC0404 2.2e-09 serine/threonine protein kinase fused to TPR repeats domain K08884; COG: COG0515 Serine/threonine protein kinase; Psort location: Cytoplasmic, score: 8.87. | Oxidoreductase; COG: NOG16874 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | 0.521 |
| EDR45948.1 | EDR45951.1 | DORFOR_02550 | DORFOR_02553 | Hypothetical protein; KEGG: cac:CAC0404 2.2e-09 serine/threonine protein kinase fused to TPR repeats domain K08884; COG: COG0515 Serine/threonine protein kinase; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; KEGG: ehi:1.t00095 0.00013 choline/ethanolamine kinase, putative K00894; COG: NOG22933 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | 0.457 |
| EDR45948.1 | EDR45952.1 | DORFOR_02550 | DORFOR_02554 | Hypothetical protein; KEGG: cac:CAC0404 2.2e-09 serine/threonine protein kinase fused to TPR repeats domain K08884; COG: COG0515 Serine/threonine protein kinase; Psort location: Cytoplasmic, score: 8.87. | Glycosyltransferase, group 2 family protein; KEGG: sat:SYN_00376 1.1e-19 glycosyltransferase involved in cell wall biogenesis; COG: NOG10066 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | 0.474 |
| EDR45948.1 | EDR45955.1 | DORFOR_02550 | DORFOR_02557 | Hypothetical protein; KEGG: cac:CAC0404 2.2e-09 serine/threonine protein kinase fused to TPR repeats domain K08884; COG: COG0515 Serine/threonine protein kinase; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; KEGG: azo:azo2810 1.3e-06 conserved hypothetical protein K01010; COG: NOG13526 non supervised orthologous group. | 0.527 |
| EDR45949.1 | EDR45948.1 | DORFOR_02551 | DORFOR_02550 | Radical SAM domain protein; COG: COG0535 Predicted Fe-S oxidoreductases; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; KEGG: cac:CAC0404 2.2e-09 serine/threonine protein kinase fused to TPR repeats domain K08884; COG: COG0515 Serine/threonine protein kinase; Psort location: Cytoplasmic, score: 8.87. | 0.445 |
| EDR45949.1 | EDR45950.1 | DORFOR_02551 | DORFOR_02552 | Radical SAM domain protein; COG: COG0535 Predicted Fe-S oxidoreductases; Psort location: Cytoplasmic, score: 8.87. | Oxidoreductase; COG: NOG16874 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | 0.726 |
| EDR45949.1 | EDR45951.1 | DORFOR_02551 | DORFOR_02553 | Radical SAM domain protein; COG: COG0535 Predicted Fe-S oxidoreductases; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; KEGG: ehi:1.t00095 0.00013 choline/ethanolamine kinase, putative K00894; COG: NOG22933 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | 0.645 |
| EDR45949.1 | EDR45952.1 | DORFOR_02551 | DORFOR_02554 | Radical SAM domain protein; COG: COG0535 Predicted Fe-S oxidoreductases; Psort location: Cytoplasmic, score: 8.87. | Glycosyltransferase, group 2 family protein; KEGG: sat:SYN_00376 1.1e-19 glycosyltransferase involved in cell wall biogenesis; COG: NOG10066 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | 0.857 |
| EDR45949.1 | EDR45953.1 | DORFOR_02551 | DORFOR_02555 | Radical SAM domain protein; COG: COG0535 Predicted Fe-S oxidoreductases; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; KEGG: sat:SYN_00363 5.2e-32 glutamate synthase [NADPH] small chain K00264; COG: COG0247 Fe-S oxidoreductase; Psort location: Cytoplasmic, score: 8.87. | 0.490 |
| EDR45949.1 | EDR45954.1 | DORFOR_02551 | DORFOR_02556 | Radical SAM domain protein; COG: COG0535 Predicted Fe-S oxidoreductases; Psort location: Cytoplasmic, score: 8.87. | SNARE-like domain protein; KEGG: pat:Patl_0395 1.8e-17 pyridine nucleotide-disulphide oxidoreductase dimerisation region K00520; COG: COG0398 Uncharacterized conserved protein; Psort location: CytoplasmicMembrane, score: 9.99. | 0.590 |
| EDR45950.1 | EDR45943.1 | DORFOR_02552 | DORFOR_02545 | Oxidoreductase; COG: NOG16874 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | AICARFT/IMPCHase bienzyme; KEGG: dme:Dmel_CG11089 3.3e-124 CG11089 K00602:K01492; COG: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); Psort location: Cytoplasmic, score: 8.87. | 0.484 |
| EDR45950.1 | EDR45948.1 | DORFOR_02552 | DORFOR_02550 | Oxidoreductase; COG: NOG16874 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; KEGG: cac:CAC0404 2.2e-09 serine/threonine protein kinase fused to TPR repeats domain K08884; COG: COG0515 Serine/threonine protein kinase; Psort location: Cytoplasmic, score: 8.87. | 0.521 |
| EDR45950.1 | EDR45949.1 | DORFOR_02552 | DORFOR_02551 | Oxidoreductase; COG: NOG16874 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | Radical SAM domain protein; COG: COG0535 Predicted Fe-S oxidoreductases; Psort location: Cytoplasmic, score: 8.87. | 0.726 |
| EDR45950.1 | EDR45951.1 | DORFOR_02552 | DORFOR_02553 | Oxidoreductase; COG: NOG16874 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; KEGG: ehi:1.t00095 0.00013 choline/ethanolamine kinase, putative K00894; COG: NOG22933 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | 0.773 |
| EDR45950.1 | EDR45952.1 | DORFOR_02552 | DORFOR_02554 | Oxidoreductase; COG: NOG16874 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | Glycosyltransferase, group 2 family protein; KEGG: sat:SYN_00376 1.1e-19 glycosyltransferase involved in cell wall biogenesis; COG: NOG10066 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | 0.732 |
| EDR45950.1 | EDR45953.1 | DORFOR_02552 | DORFOR_02555 | Oxidoreductase; COG: NOG16874 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; KEGG: sat:SYN_00363 5.2e-32 glutamate synthase [NADPH] small chain K00264; COG: COG0247 Fe-S oxidoreductase; Psort location: Cytoplasmic, score: 8.87. | 0.616 |