STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR45958.1Hypothetical protein. (183 aa)    
Predicted Functional Partners:
EDR45718.1
Iron chelate uptake ABC transporter, FeCT family, permease protein; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 0.990
cbiK
Cobalt chelatase (CbiK); KEGG: ctc:CTC00743 2.3e-45 cbiK; anaerobic cobalt chelatase cbiK K02190; COG: COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase.
    
0.974
EDR45717.1
KEGG: tde:TDE0746 1.3e-81 iron compound ABC transporter, ATP-binding protein, putative K02013; Psort location: CytoplasmicMembrane, score: 9.49.
 
 0.948
EDR45719.1
Periplasmic binding protein.
     0.935
EDR47173.1
Putative iron-only hydrogenase system regulator; COG: NOG17852 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
 0.834
EDR45720.1
Hypothetical protein; KEGG: pfa:MAL8P1.23 7.0e-14 ubiquitin-protein ligase 1, putative.
  
     0.760
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
  
  
 0.519
cobA
uroporphyrinogen-III C-methyltransferase; KEGG: cno:NT01CX_0261 1.5e-89 uroporphyrinogen III synthase/methyltransferase K00589; COG: COG1587 Uroporphyrinogen-III synthase; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.519
cobK
precorrin-6A reductase; KEGG: ctc:CTC00734 4.6e-56 cbiT; precorrin-6B methylase/decarboxylase cbiT/cbiE K03399:K02191; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.444
hisE
phosphoribosyl-ATP diphosphatase; KEGG: sao:SAOUHSC_03008 4.1e-55 imidazole glycerol phosphate synthase subunit HisF, putative K01663; COG: COG0139 Phosphoribosyl-AMP cyclohydrolase; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the PRA-PH family.
   
   0.429
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.