STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR45962.1Nitroreductase family protein; KEGG: fnu:FN1223 3.3e-21 oxygen-insensitive NAD(P)H nitroreductase / dihydropteridine reductase K00357; COG: COG0778 Nitroreductase; Psort location: Cytoplasmic, score: 8.87. (172 aa)    
Predicted Functional Partners:
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
  
 
 0.811
cobA
uroporphyrinogen-III C-methyltransferase; KEGG: cno:NT01CX_0261 1.5e-89 uroporphyrinogen III synthase/methyltransferase K00589; COG: COG1587 Uroporphyrinogen-III synthase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.811
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.554
EDR47723.1
Hypothetical protein; COG: COG0842 ABC-type multidrug transport system, permease component; Psort location: CytoplasmicMembrane, score: 9.99.
  
  
 0.526
EDR47264.1
Glyoxalase family protein; KEGG: fnu:FN0356 4.7e-38 lactoylglutathione lyase K01759; COG: COG0346 Lactoylglutathione lyase and related lyases.
  
    0.525
EDR47722.1
Hypothetical protein; COG: COG0842 ABC-type multidrug transport system, permease component; Psort location: CytoplasmicMembrane, score: 10.00.
  
    0.520
EDR45960.1
Exonuclease, DNA polymerase III, epsilon subunit family; KEGG: tte:TTE1398 4.0e-33 polC; DNA polymerase III alpha subunit, the Gram-positive type K03763; COG: COG2176 DNA polymerase III, alpha subunit (gram-positive type); Psort location: Cytoplasmic, score: 8.87.
       0.505
EDR45961.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.505
EDR48060.1
AMP-binding enzyme; KEGG: bca:BCE_0965 4.7e-70 AMP-binding protein K01897; COG: COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; Psort location: Cytoplasmic, score: 9.98.
  
   0.445
EDR45604.1
AMP-binding enzyme; KEGG: bha:BH3104 1.2e-57 long-chain fatty-acid-CoA ligase K01897; COG: COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; Psort location: CytoplasmicMembrane, score: 9.49.
   
   0.445
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.