close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR46108.1ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bcz:BCZK4751 3.7e-31 resE; sensor histidine kinase; COG: COG5002 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. (393 aa)    
Predicted Functional Partners:
EDR46109.1
KEGG: rha:RHA1_ro05622 2.2e-33 response regulator (protein-glutamate methylesterase) K07669; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
  0.970
EDR46107.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99.
 
    0.912
EDR46105.1
KEGG: noc:Noc_2142 3.0e-36 ABC transporter, ATPase subunit; COG: COG1131 ABC-type multidrug transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 9.49.
 
     0.891
EDR48218.1
Hypothetical protein; KEGG: abo:ABO_0442 8.9e-07 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 8.87.
   
 0.857
EDR46675.1
KEGG: rha:RHA1_ro05622 6.1e-38 response regulator (protein-glutamate methylesterase) K07669; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
  
  0.850
EDR48497.1
Response regulator receiver domain protein; KEGG: ava:Ava_3369 6.0e-31 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
  
  0.824
EDR48272.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC00629 7.5e-72 spaK; subtilin biosynthesis sensor protein SpaK; COG: COG0642 Signal transduction histidine kinase.
  
  
 
0.795
EDR48498.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 1.3e-42 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase.
  
 
   0.765
EDR46677.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99.
 
    0.752
EDR48500.1
Efflux ABC transporter, permease protein; COG: COG0577 ABC-type antimicrobial peptide transport system, permease component; Psort location: CytoplasmicMembrane, score: 9.99.
  
     0.698
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.