Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDR46145.1Sigma-70, region 4; KEGG: btl:BALH_3229 3.7e-06 sigW; RNA polymerase sigma-70 factor, ECF subfamily K00960; COG: NOG16920 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (139 aa)    
Predicted Functional Partners:
EDR46146.1
Hypothetical protein; COG: NOG21981 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
     0.908
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
 
 0.830
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
 
 0.814
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.791
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.790
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.790
EDR46462.1
Hypothetical protein; COG: NOG21981 non supervised orthologous group.
 
     0.785
EDR46136.1
Hypothetical protein; COG: NOG08579 non supervised orthologous group.
 
     0.708
EDR46134.1
Hypothetical protein; KEGG: xtr:407915 0.0052 ppig; peptidyl-prolyl isomerase G (cyclophilin G) K01802; COG: NOG05967 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 10.00.
 
     0.664
EDR46874.1
Hypothetical protein; COG: NOG21981 non supervised orthologous group.
 
     0.650
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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