STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (214 aa)    
Predicted Functional Partners:
EDR47968.1
Phosphoribulokinase/uridine kinase family protein; KEGG: cpe:CPE1347 1.3e-122 probable uridine kinase K00876; COG: COG0572 Uridine kinase; Psort location: Cytoplasmic, score: 8.87.
  
 0.987
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.973
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.956
pyrF
KEGG: blo:BL0791 4.1e-64 pyrF; orotidine 5'-phosphate decarboxylase K01591; COG: COG0284 Orotidine-5-phosphate decarboxylase; Psort location: Cytoplasmic, score: 8.87; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 
 0.934
udp
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.
     
 0.873
deoD
KEGG: bcl:ABC4021 8.9e-76 deoD; purine-nucleoside phosphorylase K03784; COG: COG0813 Purine-nucleoside phosphorylase; Psort location: Cytoplasmic, score: 8.87.
    
  0.860
EDR47654.1
5'-nucleotidase, C-terminal domain protein; KEGG: afu:AF0876 6.5e-57 nt5; 5'-nucleotidase (nt5) K01081; COG: COG0737 5-nucleotidase/2,3-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family.
     
 0.851
EDR47283.1
Hypothetical protein; COG: COG2313 Uncharacterized enzyme involved in pigment biosynthesis; Psort location: Cytoplasmic, score: 8.87.
    
  0.842
EDR46178.1
Cytidine and deoxycytidylate deaminase zinc-binding region; KEGG: cpe:CPE1066 4.1e-48 dCMP deaminase K01493; COG: COG2131 Deoxycytidylate deaminase; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.830
rpiB
KEGG: sth:STH2337 5.9e-56 ribose 5-phosphate isomerase K01808; COG: COG0698 Ribose 5-phosphate isomerase RpiB; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.799
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.