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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR46207.1Hypothetical protein; KEGG: fnu:FN2033 9.3e-10 guanylate kinase K00942; COG: COG0194 Guanylate kinase; Psort location: Cytoplasmic, score: 8.87. (195 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.957
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.916
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
  
 
 0.916
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.894
holB
DNA polymerase III, delta' subunit; KEGG: tte:TTE0097 2.3e-52 holB; ATPase involved in DNA replication K02341; COG: COG2812 DNA polymerase III, gamma/tau subunits; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.883
pyk
Pyruvate kinase; KEGG: tte:TTE1815 2.8e-136 pykF; pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.874
hpt
KEGG: tte:TTE2394 5.0e-43 hpt; hypoxanthine-guanine phosphoribosyltransferase K00760; COG: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Psort location: Cytoplasmic, score: 9.98; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.871
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
   
 0.870
EDR47654.1
5'-nucleotidase, C-terminal domain protein; KEGG: afu:AF0876 6.5e-57 nt5; 5'-nucleotidase (nt5) K01081; COG: COG0737 5-nucleotidase/2,3-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family.
    
  0.850
EDR46206.1
Orn/Lys/Arg decarboxylase, major domain protein; KEGG: tte:TTE0093 2.3e-68 ldcC; Arginine/lysine/ornithine decarboxylases K01582; COG: COG1982 Arginine/lysine/ornithine decarboxylases; Psort location: Cytoplasmic, score: 8.87.
       0.833
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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