STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR46216.1Sigma-70 region 2; KEGG: btl:BALH_3229 7.4e-17 sigW; RNA polymerase sigma-70 factor, ECF subfamily K00960; COG: COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Psort location: Cytoplasmic, score: 8.87. (168 aa)    
Predicted Functional Partners:
EDR46217.1
COG: COG4880 Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats.
 
     0.874
EDR46215.1
Hypothetical protein.
       0.773
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.680
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.665
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.586
EDR46218.1
Tetratricopeptide repeat protein; KEGG: mpe:MYPE6470 3.3e-58 parC; DNA topoisomerase IV subunit A K02621; COG: KOG1181 FOG: Low-complexity; Psort location: Extracellular, score: 7.62.
  
    0.546
EDR46214.1
Aconitase domain protein; KEGG: ecp:ECP_0784 6.2e-242 aconitate hydratase K01680; COG: COG1048 Aconitase A; Psort location: Cytoplasmic, score: 9.98.
       0.470
EDR46050.1
Sigma-70 region 2; KEGG: reh:H16_A2563 5.8e-17 rpoE1; DNA-directed RNA polymerase sigma subunit (RpoE,sigma24) K00960; COG: COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Psort location: Cytoplasmic, score: 8.87; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.433
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.418
EDR46213.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
 
     0.414
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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