STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR46221.1Thioredoxin; KEGG: ava:Ava_4761 6.9e-14 thioredoxin K03671; COG: COG0526 Thiol-disulfide isomerase and thioredoxins; Psort location: Cytoplasmic, score: 9.98; Belongs to the thioredoxin family. (105 aa)    
Predicted Functional Partners:
EDR46347.1
Putative thioredoxin; KEGG: eci:UTI89_C4335 4.5e-17 trxA; thioredoxin 1 K03671; COG: COG0526 Thiol-disulfide isomerase and thioredoxins; Psort location: Cytoplasmic, score: 9.98; Belongs to the thioredoxin family.
  
     0.773
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.738
EDR45562.1
Thioredoxin; KEGG: eci:UTI89_C4335 3.9e-11 trxA; thioredoxin 1 K03671; COG: COG0526 Thiol-disulfide isomerase and thioredoxins; Psort location: Cytoplasmic, score: 8.87.
  
     0.682
EDR47993.1
Thioredoxin; KEGG: eci:UTI89_C4335 2.2e-10 trxA; thioredoxin 1 K03671; COG: COG0526 Thiol-disulfide isomerase and thioredoxins; Psort location: Cytoplasmic, score: 8.87.
  
     0.673
EDR48157.1
Hypothetical protein; KEGG: lsl:LSL_0888 3.1e-41 arsC; arsenate reductase; COG: COG0394 Protein-tyrosine-phosphatase; Psort location: Cytoplasmic, score: 8.87; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
 0.653
EDR46222.1
Hypothetical protein.
       0.563
EDR46220.1
Hypothetical protein; KEGG: cal:orf19.4072 2.1e-05 HYR10; similar to cell surface flocculin K01186; COG: COG4086 Predicted secreted protein.
       0.492
EDR47459.1
COG: COG3209 Rhs family protein; Psort location: Cellwall, score: 9.17.
    
   0.484
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
 
  
 0.483
trxB
KEGG: chy:CHY_2389 2.6e-78 trxB2; thioredoxin-disulfide reductase K00384; COG: COG0492 Thioredoxin reductase; Psort location: Cytoplasmic, score: 9.65.
  
 
 0.479
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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