STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR46241.1Hypothetical protein; COG: NOG13728 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (295 aa)    
Predicted Functional Partners:
EDR46029.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: chu:CHU_3089 1.7e-59 evgS; sensor histidine kinase/response regulator fusion protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.82.
  
 
 0.756
EDR45721.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
     0.637
EDR48218.1
Hypothetical protein; KEGG: abo:ABO_0442 8.9e-07 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 8.87.
 
    0.598
EDR45838.1
Hypothetical protein; COG: COG5464 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
 
     0.565
EDR47865.1
Hypothetical protein; COG: NOG08812 non supervised orthologous group.
  
     0.543
EDR48602.1
Resolvase, N-terminal domain protein; COG: COG1961 Site-specific recombinases, DNA invertase Pin homologs; Psort location: Cytoplasmic, score: 8.87.
  
     0.534
EDR45761.1
Hypothetical protein; KEGG: poy:PAM621 0.0045 uvrD; ATP-dependent DNA helicase K03657; COG: KOG1181 FOG: Low-complexity; Psort location: Cytoplasmic, score: 8.87.
 
     0.532
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.531
EDR48400.1
Hypothetical protein; COG: COG5464 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
 
     0.528
EDR46240.1
Hypothetical protein.
       0.526
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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