STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR46272.1Methyltransferase, MtaA/CmuA family; KEGG: swo:Swol_0417 1.1e-59 uroporphyrinogen decarboxylase K01599; COG: COG0407 Uroporphyrinogen-III decarboxylase; Psort location: Cytoplasmic, score: 8.87. (353 aa)    
Predicted Functional Partners:
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
  
 0.949
cobA
uroporphyrinogen-III C-methyltransferase; KEGG: cno:NT01CX_0261 1.5e-89 uroporphyrinogen III synthase/methyltransferase K00589; COG: COG1587 Uroporphyrinogen-III synthase; Psort location: Cytoplasmic, score: 8.87.
  
 0.949
EDR45725.1
B12 binding domain protein; KEGG: mbu:Mbur_1365 1.1e-43 corrinoid methyltransferase K00548; Psort location: Cytoplasmic, score: 8.87.
 
 0.946
EDR45723.1
2Fe-2S iron-sulfur cluster binding domain protein; KEGG: son:SO0907 2.0e-10 nqrF-1; NADH:ubiquinone oxidoreductase, Na translocating, beta subunit K00351; Psort location: Cytoplasmic, score: 8.87.
 
    0.786
EDR45722.1
Hypothetical protein; KEGG: mmp:MMP0831 5.5e-21 mtbA; uroporphyrinogen decarboxylase (URO-D) K00599; Psort location: Cytoplasmic, score: 8.87.
  
     0.771
EDR45873.1
Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
 
 0.760
hemZ
KEGG: cpe:CPE1935 9.2e-90 hemZ; probable coproporphyrinogen III oxidase K02495; COG: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Psort location: Cytoplasmic, score: 9.98.
  
 
 0.726
EDR46273.1
Methyltransferase, MtaA/CmuA family; KEGG: swo:Swol_0417 9.7e-63 uroporphyrinogen decarboxylase K01599; COG: COG0407 Uroporphyrinogen-III decarboxylase; Psort location: Cytoplasmic, score: 8.87.
 
 
 
0.716
EDR45735.1
Hypothetical protein; KEGG: swo:Swol_0417 1.7e-35 uroporphyrinogen decarboxylase K01599; Psort location: Cytoplasmic, score: 8.87.
 
 
 
0.529
EDR46495.1
Methyltransferase, MtaA/CmuA family; KEGG: swo:Swol_0417 2.1e-76 uroporphyrinogen decarboxylase K01599; COG: COG0407 Uroporphyrinogen-III decarboxylase; Psort location: Cytoplasmic, score: 8.87.
 
 
 
0.493
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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