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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR46352.1Siroheme synthase domain protein; KEGG: plu:plu0708 1.1e-28 cysG; sirohaem synthase K02302:K02303:K02304; COG: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); Psort location: Cytoplasmic, score: 8.87. (196 aa)    
Predicted Functional Partners:
cobA
uroporphyrinogen-III C-methyltransferase; KEGG: cno:NT01CX_0261 1.5e-89 uroporphyrinogen III synthase/methyltransferase K00589; COG: COG1587 Uroporphyrinogen-III synthase; Psort location: Cytoplasmic, score: 8.87.
 
 0.999
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
 
 
 0.998
cobM
KEGG: mja:MJ1578 9.8e-70 cbiF; precorrin-4 C11-methyltransferase K03396; Psort location: Cytoplasmic, score: 8.87.
  
 0.973
cobK
precorrin-6A reductase; KEGG: ctc:CTC00734 4.6e-56 cbiT; precorrin-6B methylase/decarboxylase cbiT/cbiE K03399:K02191; Psort location: Cytoplasmic, score: 8.87.
   
 0.946
EDR48308.1
Putative cobalt-factor II C(20)-methyltransferase; KEGG: fnu:FN0959 7.6e-31 precorrin-2 C20-methyltransferase K03394; COG: COG2243 Precorrin-2 methylase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.875
cbiK
Cobalt chelatase (CbiK); KEGG: ctc:CTC00743 2.3e-45 cbiK; anaerobic cobalt chelatase cbiK K02190; COG: COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase.
    
 0.818
EDR46351.1
BioY family protein; KEGG: oih:OB1717 5.4e-14 biotin synthase K01012; COG: COG1268 Uncharacterized conserved protein; Psort location: CytoplasmicMembrane, score: 9.99.
       0.780
EDR46345.1
Nitrite/sulfite reductase ferredoxin domain protein; KEGG: mac:MA3439 1.3e-60 sulfite reductase, beta subunit K00439; COG: COG2221 Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits; Psort location: Cytoplasmic, score: 9.98; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
     0.772
EDR46350.1
Hypothetical protein; COG: COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily.
       0.721
EDR46349.1
ThiF family protein; KEGG: hpa:HPAG1_0799 3.4e-60 thiamine biosynthesis protein; COG: COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.716
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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