Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDR46418.1Hypothetical protein; COG: NOG13858 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (204 aa)    
Predicted Functional Partners:
EDR46161.1
COG: COG1272 Predicted membrane protein, hemolysin III homolog; Psort location: CytoplasmicMembrane, score: 9.99.
 
  
 0.608
EDR46422.1
Response regulator receiver domain protein; KEGG: eci:UTI89_C0698 1.8e-45 kdpE; transcriptional regulatory protein KdpE K07667; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
   
   0.558
EDR46419.1
Hypothetical protein.
       0.518
EDR46420.1
Hypothetical protein.
       0.518
EDR46421.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: lin:lin2827 2.5e-53 similar to the two components sensor protein kdpD K07646; COG: COG2205 Osmosensitive K+ channel histidine kinase; Psort location: CytoplasmicMembrane, score: 9.99.
       0.518
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.475
pcrA
KEGG: efa:EF0721 4.4e-186 pcrA; ATP-dependent DNA helicase PcrA K03657; COG: COG0210 Superfamily I DNA and RNA helicases; Psort location: Cytoplasmic, score: 8.87.
       0.475
EDR47433.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
     0.470
EDR46425.1
Hypothetical protein.
 
     0.430
glnA
KEGG: chy:CHY_0704 5.6e-154 glnA1; glutamine synthetase K01915; COG: COG0174 Glutamine synthetase; Psort location: Cytoplasmic, score: 9.98.
  
 
 0.428
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: low (18%) [HD]