Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rumA-223S rRNA (uracil-5-)-methyltransferase RumA; KEGG: ctc:CTC01941 4.5e-120 tRNA (uracil-5-) -methyltransferase K00557; COG: COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Psort location: Cytoplasmic, score: 8.87; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (461 aa)    
Predicted Functional Partners:
EDR46425.1
Hypothetical protein.
       0.703
EDR46427.1
Hypothetical protein; COG: COG1432 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
       0.683
EDR46426.1
Hypothetical protein; Psort location: Extracellular, score: 8.82.
       0.678
pcrA
KEGG: efa:EF0721 4.4e-186 pcrA; ATP-dependent DNA helicase PcrA K03657; COG: COG0210 Superfamily I DNA and RNA helicases; Psort location: Cytoplasmic, score: 8.87.
  
    0.501
rsmI
S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
  
  
 0.434
EDR46429.1
ParB-like protein; KEGG: pub:SAR11_0354 1.5e-09 parB; chromosome partitioning protein K03497; COG: COG1475 Predicted transcriptional regulators; Psort location: Cytoplasmic, score: 8.87; Belongs to the ParB family.
       0.421
EDR46991.1
ABC transporter, ATP-binding protein; KEGG: cch:Cag_0334 3.0e-100 ATPase K06158; COG: COG0488 ATPase components of ABC transporters with duplicated ATPase domains; Psort location: CytoplasmicMembrane, score: 10.00.
  
    0.405
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
  
 0.404
EDR46423.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.403
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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