Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EDR46463.1Sigma-70, region 4; COG: NOG16920 non supervised orthologous group. (138 aa)    
Predicted Functional Partners:
EDR46462.1
Hypothetical protein; COG: NOG21981 non supervised orthologous group.
 
     0.948
EDR46465.1
DNA-binding helix-turn-helix protein; COG: NOG37851 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
     0.807
EDR46146.1
Hypothetical protein; COG: NOG21981 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
     0.730
EDR46874.1
Hypothetical protein; COG: NOG21981 non supervised orthologous group.
 
     0.727
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.655
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.652
EDR46470.1
Hypothetical protein; COG: NOG08579 non supervised orthologous group.
  
     0.637
EDR46472.1
Hypothetical protein; KEGG: sha:SH0168 3.0e-06 lip; putative triacylglycerol lipase precursor; K01046 triacylglycerol lipase K01046; COG: NOG05967 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 10.00.
  
     0.627
EDR46880.1
DNA-binding helix-turn-helix protein; COG: NOG37851 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
     0.598
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.584
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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